Genome-Wide Identification of Allele-Specific Gene Expression in a Parent-of-Origin Specific Manner.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9865-4_11
Abstract: Upon fertilization, normal endosperm and embryo development require the contribution of both the maternal and paternal genomes. However, certain genes are expressed in a parent-of-origin-dependent manner, an epigenetic phenomenon known as genomic imprinting. Despite the… read more here.
Keywords: manner; expression parent; parent origin; gene expression ... See more keywords
Pepducin ICL1-9-Mediated β2-Adrenergic Receptor-Dependent Cardiomyocyte Contractility Occurs in a Gi Protein/ROCK/PKD-Sensitive Manner
Sign Up to like & getrecommendations! Published in 2022 at "Cardiovascular Drugs and Therapy"
DOI: 10.1007/s10557-021-07299-4
Abstract: β-Adrenergic receptors (βAR) are essential targets for the treatment of heart failure (HF); however, chronic use of βAR agonists as positive inotropes to increase contractility in a Gs protein-dependent manner is associated with increased mortality.… read more here.
Keywords: icl1 mediated; contractility; icl1; cardiomyocyte contractility ... See more keywords
Effect of hydrogel elasticity and ephrinB2-immobilized manner on Runx2 expression of human mesenchymal stem cells.
Sign Up to like & getrecommendations! Published in 2017 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2017.03.016
Abstract: The objective of this study is to design the manner of ephrinB2 immobilized onto polyacrylamide (PAAm) hydrogels with varied elasticity and evaluate the effect of hydrogels elasticity and the immobilized manner of ephrinB2 on the… read more here.
Keywords: manner; elasticity; ephrinb2 immobilized; runx2 expression ... See more keywords
Bisphenol A inhibits compound action potentials in the frog sciatic nerve in a manner independent of estrogen receptors
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2017.03.006
Abstract: Although the endocrine disruptor bisphenol A (BPA) is reported to inhibit nerve conduction, the underlying mechanisms are unclear. Therefore, in the present study, we examined the effect of BPA on compound action potentials (CAPs) recorded… read more here.
Keywords: manner; bpa; estrogen; sciatic nerve ... See more keywords
β-Endorphin and sex differentially modulate the response to EtOH in a site-specific manner
Sign Up to like & getrecommendations! Published in 2020 at "Brain Research"
DOI: 10.1016/j.brainres.2020.146845
Abstract: Abstract The effects of alcohol are multifaceted, involving brain circuits regulating reward, motivation, and stress, frequently via the endogenous opioid, beta-endorphin (β-E). It is currently unknown how alcohol affects neural circuit activation in females and… read more here.
Keywords: manner; sex; etoh; brain ... See more keywords
Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner
Sign Up to like & getrecommendations! Published in 2018 at "Cell"
DOI: 10.1016/j.cell.2017.11.042
Abstract: Summary Microglia are embryonically seeded macrophages that contribute to brain development, homeostasis, and pathologies. It is thus essential to decipher how microglial properties are temporally regulated by intrinsic and extrinsic factors, such as sexual identity… read more here.
Keywords: manner; adult; prenatal adult; microbiome influences ... See more keywords
Apolipoprotein A-IV constrains HPA and behavioral stress responsivity in a strain-dependent manner
Sign Up to like & getrecommendations! Published in 2017 at "Psychoneuroendocrinology"
DOI: 10.1016/j.psyneuen.2017.08.025
Abstract: There is a critical gap in our knowledge of the mechanisms that govern interactions between daily life experiences (e.g., stress) and metabolic diseases, despite evidence that stress can have profound effects on cardiometabolic health. Apolipoprotein… read more here.
Keywords: manner; apolipoprotein constrains; stress; constrains hpa ... See more keywords
Human chemosignals modulate emotional perception of biological motion in a sex-specific manner
Sign Up to like & getrecommendations! Published in 2019 at "Psychoneuroendocrinology"
DOI: 10.1016/j.psyneuen.2018.10.014
Abstract: Androsta-4,16,-dien-3-one and estra-1,3,5(10),16-tetraen-3-ol have previously been shown to communicate opposite sex information that is differently effective to the two sex groups. The current study critically examines if the two human steroids could facilitate interactions with… read more here.
Keywords: manner; emotional perception; perception; human chemosignals ... See more keywords
Bisphenol A impairs the memory function and glutamatergic homeostasis in a sex‐dependent manner in mice: Beneficial effects of diphenyl diselenide
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2017.05.035
Abstract: &NA; Bisphenol A (BPA) is a compound integrated in commodities, which consequently increases the human exposure to this toxicant. The deleterious effects of BPA exposure during periods of brain development have been documented mainly concerning… read more here.
Keywords: manner; sex dependent; exposure; mice ... See more keywords
The other side of the corona: nanoparticles inhibit the protease taspase1 in a size-dependent manner.
Sign Up to like & getrecommendations! Published in 2020 at "Nanoscale"
DOI: 10.1039/d0nr01631d
Abstract: When nanoparticles enter a physiological environment, they rapidly adsorb biomolecules, in particular cellular proteins. This biological coating, the so-called nanoparticle protein corona, undoubtedly affects the biological identity and potential cytotoxicity of the nanomaterial. To elucidate… read more here.
Keywords: side corona; manner; nanoparticles inhibit; protease taspase1 ... See more keywords
Universal formulation of central-moments-based lattice Boltzmann method with external forcing for the simulation of multiphysics phenomena
Sign Up to like & getrecommendations! Published in 2019 at "Physics of Fluids"
DOI: 10.1063/1.5124719
Abstract: The cascaded or central-moments-based lattice Boltzmann method (CM-LBM) is a robust alternative to the more conventional Bhatnagar-Gross-Krook-LBM for the simulation of high-Reynolds number flows. Unfortunately, its original formulation makes its extension to a broader range… read more here.
Keywords: manner; methodology; physics; lattice boltzmann ... See more keywords