Articles with "mannich bases" as a keyword



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Epoxy adhesive with high underwater adhesion and stability based on low viscosity modified Mannich bases

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Published in 2018 at "Journal of Applied Polymer Science"

DOI: 10.1002/app.45688

Abstract: A series of Mannich base curing agents were synthesized by using different structured phenols and amines. The phenols were phenol, o-cresol, and nonylphenol, and the amines were diethylenetriamine, m-xylylenediamine, and JEFFAMINE D230 polyetheramine. The chemical… read more here.

Keywords: underwater adhesion; adhesion; mannich bases; epoxy adhesive ... See more keywords
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Some Novel Mannich Bases of 5‐(3,4‐Dichlorophenyl)‐1,3,4‐oxadiazole‐2(3H)‐one and Their Anti‐Inflammatory Activity

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Published in 2017 at "Archiv der Pharmazie"

DOI: 10.1002/ardp.201700153

Abstract: Non‐steroidal anti‐inflammatory drugs (NSAIDs), which are widely used for the treatment of rheumatic arthritis, pain, and many different types of inflammatory disorders, cause serious gastrointestinal (GI) side effects. The free carboxylic acid group existing on… read more here.

Keywords: anti inflammatory; activity; mannich bases; inflammatory ... See more keywords
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Electrochemical Oxidative C(sp3 )-H/N-H Cross-Coupling for N-Mannich Bases with Hydrogen Evolution.

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Published in 2018 at "ChemSusChem"

DOI: 10.1002/cssc.201802676

Abstract: N-Mannich bases are an important structure in various functional molecules. A new protocol to synthesize N-Mannich bases was established through electrochemical external-oxidant-free C(sp3 )-H/N-H cross-coupling with hydrogen evolution. Various N-methylanilines were explored in this transformation.… read more here.

Keywords: cross coupling; hydrogen evolution; sp3 cross; mannich bases ... See more keywords
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Synthesis, in vitro antiproliferative activity, antioxidant activity and molecular modeling studies of new carbazole Mannich bases

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Published in 2017 at "Medicinal Chemistry Research"

DOI: 10.1007/s00044-017-1927-5

Abstract: A new class of carbazole Mannich bases were synthesized from 4-hydroxycarbazole by reacting with aromatic aldehydes and cyclic amines under mild reaction conditions in good yields. The method does not require column chromatographic purification for… read more here.

Keywords: carbazole mannich; mannich bases; vitro antiproliferative; antiproliferative activity ... See more keywords
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Reactions of naphthalen-2-ol Mannich bases with β-aminoacrylonitriles and methyl 3-morpholinoacrylate

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Published in 2020 at "Chemistry of Heterocyclic Compounds"

DOI: 10.1007/s10593-020-02695-4

Abstract: 3-Amino-2,3-dihydro-1 H -benzo[ f ]chromenes and 2-[(2-hydroxynaphthalen-1-yl)methyl]-2,3-dihydro-1 H -benzo[ f ]chromene-2-carbonitriles were obtained via the reaction of naphthalen-2-ol Mannich bases with β-aminoacrylonitriles and methyl 3-morpholinoacrylate as products of [4+2] cycloaddition of push-pull olefins to the… read more here.

Keywords: bases aminoacrylonitriles; reactions naphthalen; mannich bases; naphthalen mannich ... See more keywords
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New phenolic Mannich bases with piperazines and their bioactivities.

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Published in 2019 at "Bioorganic chemistry"

DOI: 10.1016/j.bioorg.2019.103057

Abstract: In this study, new Mannich bases, 2-(4-hydroxy-3-methoxy-5-((substitutedpiperazin-1-yl)methyl)benzylidene)-2,3-dihydro-1H-inden-1-one (1, 2, 4, 5, 8), 2-(3-((substituted)piperazin-1-yl)methyl)-4-hydroxy-5-methoxybenzylidene)-2,3-dihydro-1H-inden-1-one (3, 6, 7) were synthesized with the reaction of vanilin derived chalcone compound (2-(4-hydroxy-3-methoxybenzylidene)indan-1-one), paraformaldehyde and suitable amine in 1:1.2:1 mol ratios.… read more here.

Keywords: new phenolic; phenolic mannich; bases piperazines; mannich bases ... See more keywords
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Synthesis and biological evaluation of some new mono Mannich bases with piperazines as possible anticancer agents and carbonic anhydrase inhibitors.

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Published in 2019 at "Bioorganic chemistry"

DOI: 10.1016/j.bioorg.2019.103095

Abstract: New mono Mannich bases, (2-(4-hydroxy-3-((4-substituephenylpiperazin-1-yl)methyl)benzylidene)-2,3-dihydro-1H-inden-1-one), were prepared to evaluate their cytotoxic/anticancer properties and also their inhibitory effects on human carbonic anhydrase I and II isoenzymes (hCA I and II). Amine part was changed as [N-phenylpiperazine… read more here.

Keywords: carbonic anhydrase; mono mannich; new mono; mannich bases ... See more keywords
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Post-synthetic modification of MIL-125 with bis-quinoline Mannich bases for removal of heavy metals from wastewater

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Published in 2019 at "Microporous and Mesoporous Materials"

DOI: 10.1016/j.micromeso.2018.12.018

Abstract: Abstract Ti-based metal-organic frameworks (NH2-MIL-125) were post synthetic modified through a facile strategy using bis-quinoline Mannich bases producing MIL-125-HQ. The modified material (MIL-125-HQ) was used as an absorbent for uptake of the heavy metals from… read more here.

Keywords: mil 125; quinoline; mannich bases; bis quinoline ... See more keywords
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An experimental work on radiation protection features of some bioactive compounds of Mannich bases

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Published in 2020 at "Radiation Physics and Chemistry"

DOI: 10.1016/j.radphyschem.2020.108986

Abstract: Abstract In the present research, seven Mannich bases, bioactive compounds, as anticancer drug proposed which have different chemical composition has been studied comprehensively in terms of photons and charged particles protecting features. Aryl part of… read more here.

Keywords: protection; experimental work; mannich bases; work radiation ... See more keywords
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Structure–Activity Relationships of 8-Hydroxyquinoline-Derived Mannich Bases with Tertiary Amines Targeting Multidrug-Resistant Cancer

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Published in 2022 at "Journal of Medicinal Chemistry"

DOI: 10.1021/acs.jmedchem.2c00076

Abstract: A recently proposed strategy to overcome multidrug resistance (MDR) in cancer is to target the collateral sensitivity of otherwise resistant cells. We designed a library of 120 compounds to explore the chemical space around previously… read more here.

Keywords: derived mannich; multidrug; mannich bases; activity ... See more keywords
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Synthesis and Corrosion Inhibition Performance of Mannich Bases on Mild Steel in Lactic Acid Media

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Published in 2022 at "ACS Omega"

DOI: 10.1021/acsomega.2c03545

Abstract: Heterocyclic Mannich bases, N-(3-oxo-3-phenylpro-pyl)thiazol-2-aminium chloride (DTZA) and N-(3-oxo-3-phenylpropyl)-1H-pyrazol-3-aminium chloride (DPZA), were developed for the corrosion inhibition of N80 steel in a 15 wt % lactic acid solution. Weight loss measurements, electrochemical techniques, surface characterization, and… read more here.

Keywords: mannich bases; lactic acid; steel lactic; corrosion inhibition ... See more keywords