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Published in 2018 at "Journal of Applied Polymer Science"
DOI: 10.1002/app.45688
Abstract: A series of Mannich base curing agents were synthesized by using different structured phenols and amines. The phenols were phenol, o-cresol, and nonylphenol, and the amines were diethylenetriamine, m-xylylenediamine, and JEFFAMINE D230 polyetheramine. The chemical…
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Keywords:
underwater adhesion;
adhesion;
mannich bases;
epoxy adhesive ... See more keywords
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Published in 2017 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.201700153
Abstract: Non‐steroidal anti‐inflammatory drugs (NSAIDs), which are widely used for the treatment of rheumatic arthritis, pain, and many different types of inflammatory disorders, cause serious gastrointestinal (GI) side effects. The free carboxylic acid group existing on…
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Keywords:
anti inflammatory;
activity;
mannich bases;
inflammatory ... See more keywords
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Published in 2018 at "ChemSusChem"
DOI: 10.1002/cssc.201802676
Abstract: N-Mannich bases are an important structure in various functional molecules. A new protocol to synthesize N-Mannich bases was established through electrochemical external-oxidant-free C(sp3 )-H/N-H cross-coupling with hydrogen evolution. Various N-methylanilines were explored in this transformation.…
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Keywords:
cross coupling;
hydrogen evolution;
sp3 cross;
mannich bases ... See more keywords
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Published in 2017 at "Medicinal Chemistry Research"
DOI: 10.1007/s00044-017-1927-5
Abstract: A new class of carbazole Mannich bases were synthesized from 4-hydroxycarbazole by reacting with aromatic aldehydes and cyclic amines under mild reaction conditions in good yields. The method does not require column chromatographic purification for…
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Keywords:
carbazole mannich;
mannich bases;
vitro antiproliferative;
antiproliferative activity ... See more keywords
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Published in 2020 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-020-02695-4
Abstract: 3-Amino-2,3-dihydro-1 H -benzo[ f ]chromenes and 2-[(2-hydroxynaphthalen-1-yl)methyl]-2,3-dihydro-1 H -benzo[ f ]chromene-2-carbonitriles were obtained via the reaction of naphthalen-2-ol Mannich bases with β-aminoacrylonitriles and methyl 3-morpholinoacrylate as products of [4+2] cycloaddition of push-pull olefins to the…
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Keywords:
bases aminoacrylonitriles;
reactions naphthalen;
mannich bases;
naphthalen mannich ... See more keywords
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Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.103057
Abstract: In this study, new Mannich bases, 2-(4-hydroxy-3-methoxy-5-((substitutedpiperazin-1-yl)methyl)benzylidene)-2,3-dihydro-1H-inden-1-one (1, 2, 4, 5, 8), 2-(3-((substituted)piperazin-1-yl)methyl)-4-hydroxy-5-methoxybenzylidene)-2,3-dihydro-1H-inden-1-one (3, 6, 7) were synthesized with the reaction of vanilin derived chalcone compound (2-(4-hydroxy-3-methoxybenzylidene)indan-1-one), paraformaldehyde and suitable amine in 1:1.2:1 mol ratios.…
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Keywords:
new phenolic;
phenolic mannich;
bases piperazines;
mannich bases ... See more keywords
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Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.103095
Abstract: New mono Mannich bases, (2-(4-hydroxy-3-((4-substituephenylpiperazin-1-yl)methyl)benzylidene)-2,3-dihydro-1H-inden-1-one), were prepared to evaluate their cytotoxic/anticancer properties and also their inhibitory effects on human carbonic anhydrase I and II isoenzymes (hCA I and II). Amine part was changed as [N-phenylpiperazine…
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Keywords:
carbonic anhydrase;
mono mannich;
new mono;
mannich bases ... See more keywords
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Published in 2019 at "Microporous and Mesoporous Materials"
DOI: 10.1016/j.micromeso.2018.12.018
Abstract: Abstract Ti-based metal-organic frameworks (NH2-MIL-125) were post synthetic modified through a facile strategy using bis-quinoline Mannich bases producing MIL-125-HQ. The modified material (MIL-125-HQ) was used as an absorbent for uptake of the heavy metals from…
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Keywords:
mil 125;
quinoline;
mannich bases;
bis quinoline ... See more keywords
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Published in 2020 at "Radiation Physics and Chemistry"
DOI: 10.1016/j.radphyschem.2020.108986
Abstract: Abstract In the present research, seven Mannich bases, bioactive compounds, as anticancer drug proposed which have different chemical composition has been studied comprehensively in terms of photons and charged particles protecting features. Aryl part of…
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Keywords:
protection;
experimental work;
mannich bases;
work radiation ... See more keywords
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Published in 2022 at "Journal of Medicinal Chemistry"
DOI: 10.1021/acs.jmedchem.2c00076
Abstract: A recently proposed strategy to overcome multidrug resistance (MDR) in cancer is to target the collateral sensitivity of otherwise resistant cells. We designed a library of 120 compounds to explore the chemical space around previously…
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Keywords:
derived mannich;
multidrug;
mannich bases;
activity ... See more keywords
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Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c03545
Abstract: Heterocyclic Mannich bases, N-(3-oxo-3-phenylpro-pyl)thiazol-2-aminium chloride (DTZA) and N-(3-oxo-3-phenylpropyl)-1H-pyrazol-3-aminium chloride (DPZA), were developed for the corrosion inhibition of N80 steel in a 15 wt % lactic acid solution. Weight loss measurements, electrochemical techniques, surface characterization, and…
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Keywords:
mannich bases;
lactic acid;
steel lactic;
corrosion inhibition ... See more keywords