Rapid alkenylation of quinoxalin-2(1H)-ones enabled by the sequential Mannich-type reaction and solar photocatalysis
Sign Up to like & getrecommendations! Published in 2021 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2021.04.016
Abstract: Abstract Herein, a rapid alkenylation of quinoxalin-2(1H)-ones enabled by a combination of Mannich-type reaction and solar photocatalysis is demonstrated. A wide range of functional groups are compatible, affording the corresponding products in moderate-to-good yields. Control… read more here.
Keywords: ones enabled; quinoxalin ones; alkenylation quinoxalin; reaction ... See more keywords
A facile synthesis of stable β-amino-N-/O-hemiacetals through a catalyst-free three-component Mannich-type reaction
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2017.02.084
Abstract: Abstract A practical, straightforward and one-step procedure for the synthesis of novel and stable β-amino-N-/O-hemiacetals (i.e. γ-aminoalcohols) is provided. The title compounds were obtained in good to excellent yields through an uncatalyzed three-component reaction by… read more here.
Keywords: stable amino; amino hemiacetals; type reaction; three component ... See more keywords
Catalytic Asymmetric Mannich Type Reaction with Tri-/Difluoro- or Trichloroacetaldimine Precursors.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b03083
Abstract: A highly efficient catalytic asymmetric Mannich type reaction of CF3-, CF2H-, or CCl3-acetaldimine precursors by a chiral primary amine is presented. This protocol provides facile access to chiral CF3-, CF2H-, or trichloroethyl amines in excellent… read more here.
Keywords: mannich type; catalytic asymmetric; type reaction; asymmetric mannich ... See more keywords
α-Halo Amides as Competent Latent Enolates: Direct Catalytic Asymmetric Mannich-Type Reaction.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b03291
Abstract: α-Halogenated carbonyl compounds are susceptible to dehalogenation and thus largely neglected as enolate precursors in catalytic enantioselective C-C bond-forming reactions. By merging the increased stability of the α-C-halogen bond of amides and the direct enolization… read more here.
Keywords: direct catalytic; type reaction; mannich type; catalytic asymmetric ... See more keywords
Concise enantioselective synthesis of non-proteinogenic α-aminoacids via an organocatalytic Mannich-type reaction.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc04909k
Abstract: A bifunctional tertiary amine-squaramide-catalyzed enantioselective Mannich-type addition of available allomaltol to N-protected aldimines was developed. The resulted adducts were readily transformed into non-proteinogenic α-amino acids and their derivatives were not easily accessible by other methods… read more here.
Keywords: enantioselective synthesis; proteinogenic aminoacids; synthesis non; concise enantioselective ... See more keywords
Enantioselective Synthesis of Difluoroalkylated Isoindolinones via Chiral Spirocyclic Phosphoric Acid Catalyzed Mannich-Type Reaction
Sign Up to like & getrecommendations! Published in 2020 at "Synlett"
DOI: 10.1055/a-1274-2959
Abstract: An enantioselective Mannich-type reaction of in situ generated cyclic ketimines with difluoroenoxysilanes catalyzed by chiral spirocyclic phosphoric acid has been developed. This methodology provides a facile route to difluoroalkyl-substituted chiral isoindolinones bearing a quaternary stereogenic… read more here.
Keywords: phosphoric acid; type reaction; chiral spirocyclic; spirocyclic phosphoric ... See more keywords
Evaluation of adsorption behavior for U(VI) and Th(IV) ions onto solidified Mannich type material
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Dispersion Science and Technology"
DOI: 10.1080/01932691.2016.1207546
Abstract: ABSTRACT Treatment of aqueous solution contaminated by uranium and thorium using a new Mannich type resin was studied. Different instrumental techniques such as elemental analysis, FTIR, and thermogravimetric analysis were employed for full characterization of… read more here.
Keywords: evaluation adsorption; mannich type; adsorption; adsorption behavior ... See more keywords
Mannich-type addition of cyclic 1,3-diketones to N-acyliminium ions: Access to aza-sugars.
Sign Up to like & getrecommendations! Published in 2023 at "Carbohydrate research"
DOI: 10.2139/ssrn.4311169
Abstract: A novel three-component strategy has been developed for the synthesis of iminosugars in good to excellent yields. This is the first report on the Mannich type addition of cyclic 1,3-diketones to aza-acetal derived from hydroxy-γ-lactone… read more here.
Keywords: aza sugars; type addition; mannich type; addition cyclic ... See more keywords
Experimental and Computational Studies Unraveling the Peculiarity of Enolizable Oxoesters in the Organocatalyzed Mannich-Type Addition to Cyclic N-Acyl Iminium Ions
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25081903
Abstract: γ− and δ-Oxoesters are easily available starting materials that have been sparingly used in some organocatalyzed reactions proceeding with a high enantioselectivity. In our experimentation we found that the use of these compounds as the… read more here.
Keywords: organocatalyzed mannich; iminium ions; mannich type; cyclic acyl ... See more keywords