Glycan Residues Balance Analysis: A novel model for the N-linked glycosylation of IgG produced by CHO cells.
Sign Up to like & getrecommendations! Published in 2019 at "Metabolic engineering"
DOI: 10.1016/j.ymben.2019.08.016
Abstract: The structure of N-linked glycosylation is a very important quality attribute for therapeutic monoclonal antibodies. Different carbon sources in cell culture media, such as mannose and galactose, have been reported to have different influences on… read more here.
Keywords: mannose galactose; glycan residues; cho cells; model ... See more keywords
Polyhydroxylated Cyclopentane β-Amino Acids Derived from d-Mannose and d-Galactose: Synthesis and Protocol for Incorporation into Peptides
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DOI: 10.1021/acsomega.1c05468
Abstract: A stereoselective synthesis of polyhydroxylated cyclopentane β-amino acids from hexoses is reported. The reaction sequence comprises, as key steps, ring-closing metathesis of a polysubstituted diene intermediate followed by the stereoselective aza-Michael functionalization of the resulting… read more here.
Keywords: cyclopentane amino; protocol incorporation; amino acids; mannose galactose ... See more keywords