Mannose receptor of Epinephelus coioides exerts antiviral activity against red-spotted grouper nervous necrosis virus and regulates apoptosis and inflammation
Sign Up to like & getrecommendations! Published in 2022 at "Aquaculture"
DOI: 10.1016/j.aquaculture.2021.737264
Abstract: Abstract Mannose receptor (MR), a pattern recognition receptor, plays a critical role in innate immune responses by binding to pathogen-associated molecular patterns. The antiviral role of MR has been described extensively in mammals but not… read more here.
Keywords: epinephelus coioides; mannose receptor; receptor; virus ... See more keywords
Expression and functional characterization of the mannose receptor (MR) from Nile tilapia (Oreochromis niloticus) in response to bacterial infection.
Sign Up to like & getrecommendations! Published in 2021 at "Developmental and comparative immunology"
DOI: 10.1016/j.dci.2021.104257
Abstract: Mannose receptor (MR) as a member of the pattern recognition receptors (PRRs) plays an important role in the immune response. In mammals, the role of MR in the regulation of phagocytosis is clarified; however, its… read more here.
Keywords: response; infection; expression; mannose receptor ... See more keywords
Sulfation at Glycopolymer Side Chains Switches Activity at the Macrophage Mannose Receptor (CD206) In Vitro and In Vivo
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c10757
Abstract: The mannose receptor (CD206) is an endocytic receptor expressed by selected innate immune cells and nonvascular endothelium, which plays a critical role in both homeostasis and pathogen recognition. Although its involvement in the development of… read more here.
Keywords: vitro vivo; cd206; mannose receptor; receptor ... See more keywords
Soluble CD163 and mannose receptor associate with chronic hepatitis B activity and fibrosis and decline with treatment
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.13849
Abstract: Liver macrophages are activated in chronic hepatitis B virus (CHB) infection and play a pivotal role in hepatic inflammation and fibrosis. However, their role during antiviral treatment is unclear. The soluble (s) macrophage activation markers,… read more here.
Keywords: fibrosis; activity fibrosis; treatment; mannose receptor ... See more keywords
The soluble mannose receptor (sMR) is elevated in alcoholic liver disease and associated with disease severity, portal hypertension, and mortality in cirrhosis patients
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0189345
Abstract: Background and aims Hepatic macrophages (Kupffer cells) are involved in the immunopathology of alcoholic liver disease (ALD). The mannose receptor (MR, CD206), expressed primarily by macrophages, mediates endocytosis, antigen presentation and T-cell activation. A soluble… read more here.
Keywords: alcoholic liver; disease; mannose receptor; smr ... See more keywords
Mannose Receptor Mediates the Activation of Chitooligosaccharides on Blunt Snout Bream (Megalobrama amblycephala) Macrophages
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.686846
Abstract: Chitooligosaccharide (COS) is an important immune enhancer and has been proven to have a variety of biological activities. Our previous research has established an M1 polarization mode by COS in blunt snout bream (Megalobrama amblycephala)… read more here.
Keywords: bream megalobrama; blunt snout; snout bream; mannose receptor ... See more keywords
Prognostic and immunotherapeutic significance of mannose receptor C type II in 33 cancers: An integrated analysis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.951636
Abstract: Background: The type 2 mannose receptor C (MRC2) is involved in tumor biological processes and plays a new role in the remodeling of the extracellular matrix turnover. Previous studies have demonstrated MRC2 expression profiling and… read more here.
Keywords: mrc2; mannose receptor; mrc2 expression; significance ... See more keywords
Rifaximin Alleviates Endotoxemia with Decreased Serum Levels of Soluble CD163 and Mannose Receptor and Partial Modification of Gut Microbiota in Cirrhotic Patients
Sign Up to like & getrecommendations! Published in 2020 at "Antibiotics"
DOI: 10.3390/antibiotics9040145
Abstract: Rifaximin is a poorly absorbable antibiotic against hepatic encephalopathy (HE). This observational study aimed to elucidate the effect of rifaximin on intestinal permeability and gut microbiota in patients with decompensated cirrhosis. Thirty patients with decompensated… read more here.
Keywords: serum levels; soluble cd163; mannose receptor; gut microbiota ... See more keywords
Spectroscopy Approach for Highly-Efficient Screening of Lectin-Ligand Interactions in Application for Mannose Receptor and Molecular Containers for Antibacterial Drugs
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DOI: 10.3390/ph15050625
Abstract: Rational search of a ligand for a specific receptor is a cornerstone of a typical drug discovery process. However, to make it more “rational” one would appreciate having detailed information on the functional groups involved… read more here.
Keywords: time; spectroscopy; mannose receptor; molecular containers ... See more keywords
Mannose receptor is an HIV restriction factor counteracted by Vpr in macrophages
Sign Up to like & getrecommendations! Published in 2020 at "eLife"
DOI: 10.7554/elife.51035
Abstract: HIV-1 Vpr is necessary for maximal HIV infection and spread in macrophages. Evolutionary conservation of Vpr suggests an important yet poorly understood role for macrophages in HIV pathogenesis. Vpr counteracts a previously unknown macrophage-specific restriction… read more here.
Keywords: hiv; restriction factor; mannose receptor; vpr ... See more keywords