A Simple Glycolipid Mimic of the Phosphatidylinositol Mannoside Core from Mycobacterium tuberculosis Inhibits Macrophage Cytokine Production
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DOI: 10.1002/cbic.201800150
Abstract: Glycolipids from Mycobacterium tuberculosis have a profound impact on the innate immune response of the host. Macrophage‐inducible C‐type lectin (Mincle) is a pattern‐recognition receptor that has been shown to bind trehalose dimycolate (TDM) from the… read more here.
Keywords: mannoside; mycobacterium; mycobacterium tuberculosis; cytokine production ... See more keywords