Conformational Behaviour of Azasugars Based on Mannuronic Acid
Sign Up to like & getrecommendations! Published in 2017 at "ChemBioChem"
DOI: 10.1002/cbic.201700080
Abstract: A set of mannuronic‐acid‐based iminosugars, consisting of the C‐5‐carboxylic acid, methyl ester and amide analogues of 1deoxymannorjirimicin (DMJ), was synthesised and their pH‐dependent conformational behaviour was studied. Under acidic conditions the methyl ester and the… read more here.
Keywords: conformational behaviour; acid; acid ester; mannuronic acid ... See more keywords
Immunomodulatory effects of M2000 (&bgr;‐D‐Mannuronic acid) on TNF‐&agr;, IL‐17 and FOXP3 gene expression in patients with inflammatory bowel disease
Sign Up to like & getrecommendations! Published in 2017 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2017.08.011
Abstract: Introduction Inflammatory bowel diseases (IBD) are immune‐mediated disorders that result from an aberrant immunological response to the gut luminal antigen in genetically susceptible patients. IBD is categorized into two serotype, Crohn's diseases (CD) and ulcerative… read more here.
Keywords: bgr mannuronic; tnf agr; mannuronic acid; expression ... See more keywords
Evaluation of the efficacy and safety of &bgr;‐d‐mannuronic acid in patients with ankylosing spondylitis: A 12‐week randomized, placebo‐controlled, phase I/II clinical trial
Sign Up to like & getrecommendations! Published in 2018 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2017.11.003
Abstract: Objective To evaluate the efficacy, safety and tolerability of &bgr;‐d‐mannuronic acid (M2000) in the treatment of ankylosing spondylitis (AS). Methods The study was a 12‐week randomized, double‐blind, placebo‐controlled, phase I/II clinical trial with 3 treatment… read more here.
Keywords: placebo; week; bgr mannuronic; mannuronic acid ... See more keywords
Promoter-Controlled Synthesis and Antigenic Evaluation of Mannuronic Acid Alginate Glycans of Pseudomonas aeruginosa.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03439
Abstract: Pseudomonas aeruginosa is a leading cause of urinary tract, pulmonary, and wound infections and is becoming increasingly resistant to antibiotics. Here, we report the iodonium- and gold(I)-promoted bimodal glycosylation of glycosyl (Z)-ynenoates for highly β-selective… read more here.
Keywords: pseudomonas aeruginosa; alginate glycans; acid; mannuronic acid ... See more keywords
Effects of Molecular Weight and Guluronic Acid/Mannuronic Acid Ratio on the Rheological Behavior and Stabilizing Property of Sodium Alginate
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DOI: 10.3390/molecules24234374
Abstract: The aim of this study was to prepare sodium alginates (SAs) with different molecular weight and G/M ratio, and characterize their rheological behaviors and emulsifying properties. The result of Fourier transform infrared (FTIR) showed that… read more here.
Keywords: guluronic acid; mannuronic acid; ratio; molecular weight ... See more keywords