LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "manufacturability" as a keyword



On the effective integration of manufacturability constraints within the multi-scale methodology for designing variable angle-tow laminates

Sign Up to like & get
recommendations! Published in 2017 at "Composite Structures"

DOI: 10.1016/j.compstruct.2016.11.018

Abstract: Abstract In this work a multi-scale two-level (MS2L) optimisation strategy for optimising VAT composites is presented. In the framework of the MS2L methodology, the design problem is split and solved into two steps. At the… read more here.

Keywords: methodology; integration manufacturability; effective integration; multi scale ... See more keywords

Manufacturability assessment in assembly processes

Sign Up to like & get
recommendations! Published in 2020 at "IFAC-PapersOnLine"

DOI: 10.1016/j.ifacol.2020.12.2801

Abstract: Abstract In this paper, there is presented the problem of assessing the manufacturability of complex products at the design stage of the manufacturing process considering the criterion of execution of assembly operations processes and production… read more here.

Keywords: manufacturability; assessment assembly; manufacturability assessment; assembly processes ... See more keywords

Assessing the Manufacturability and Critical Quality Attribute Profiles of Anti-IL-8 Immunoglobulin G Mutant Variants

Sign Up to like & get
recommendations! Published in 2024 at "Molecular Pharmaceutics"

DOI: 10.1021/acs.molpharmaceut.4c01010

Abstract: Early-phase manufacturability assessment of high-concentration therapeutic monoclonal antibodies (mAbs) involves screening of process-related risks impacting their translation into the clinic. Manufacturing a mAb at scale relies on cost-effective and robust approaches to derisk manufacturability parameters,… read more here.

Keywords: manufacturability critical; quality attribute; assessing manufacturability; manufacturability ... See more keywords

Design of next-generation therapeutic IgG4 with improved manufacturability and bioanalytical characteristics

Sign Up to like & get
recommendations! Published in 2020 at "mAbs"

DOI: 10.1080/19420862.2020.1829338

Abstract: ABSTRACT Manufacturability of immunoglobulin G4 (IgG4) antibodies from the Chemistry, Manufacture, and Controls (CMC) perspective has received little attention during early drug discovery. Despite the success of protein engineering in improving antibody biophysical properties, a… read more here.

Keywords: igg4; design; generation therapeutic; next generation ... See more keywords

Molecule Formats of B-Cell Targeting Biologics: Applications in Autoimmune Disease Treatment and Impacts on Manufacturability

Sign Up to like & get
recommendations! Published in 2025 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics17040495

Abstract: The targeting of B-lymphocyte cells has emerged as one of the most pivotal strategies in the management of autoimmune diseases. This review provides an overview of protein therapeutics illustrating their direct and indirect effects on… read more here.

Keywords: molecule formats; cell targeting; formats cell; targeting biologics ... See more keywords