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   Articles with "maoa" as a keyword



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Association of the MAOA-uVNTR polymorphism with psychopathic traits may change from childhood to adolescence

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recommendations! Published in 2022 at "European Archives of Psychiatry and Clinical Neuroscience"

DOI: 10.1007/s00406-021-01370-9

Abstract: Psychopathic traits can lead to violence, making it a serious public health concern. Genetic factors contribute to the aetiology of psychopathy. We examined whether monoamine oxidase A (MAOA-uVNTR) was associated with psychopathic traits measured quantitatively… read more here.

Keywords: polymorphism psychopathic; association maoa; psychopathic traits; maoa ... See more keywords
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Monoamine oxidase A genotype and methylation moderate the association of maltreatment and aggressive behaviour

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recommendations! Published in 2020 at "Behavioural Brain Research"

DOI: 10.1016/j.bbr.2020.112476

Abstract: BACKGROUND The association between childhood maltreatment and subsequent aggressive behaviour is modified by monoamine oxidase A (MAOA) functional polymorphism (MAOA-uVNTR) genotype, MAOA-Long (MAOA-L) in females, MAOA-Short (MAOA-S) in males. Childhood maltreatment is associated with differential… read more here.

Keywords: maltreatment aggressive; methylation; aggressive behaviour; maoa ... See more keywords

MAOA genotype modulates default mode network deactivation during inhibitory control

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recommendations! Published in 2018 at "Biological Psychology"

DOI: 10.1016/j.biopsycho.2018.08.006

Abstract: It has been demonstrated, in a long line of research, that the low-activity genotype of the monoamine oxidase A (MAOA) gene is associated with aggression. Previous work has linked impaired response inhibition to aggression, but… read more here.

Keywords: network; default mode; control; maoa genotype ... See more keywords

Does MAOA increase susceptibility to prenatal stress in young children?

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recommendations! Published in 2017 at "Neurotoxicology and teratology"

DOI: 10.1016/j.ntt.2017.01.005

Abstract: BACKGROUND We previously demonstrated a gene-by-prenatal-environment interaction whereby the monoamine oxidase A gene (MAOA) modified the impact of prenatal tobacco exposure (PTE) on adolescent disruptive behavior (DB), with the MAOA risk genotype varying by sex.… read more here.

Keywords: pse; prenatal stress; exposure; sex ... See more keywords

Addressing the serotonin hypothesis of depression through analyses of genetics, methylation and metabolite variations in glioma patients

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recommendations! Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-25464-9

Abstract: Serotonin and serotonin metabolism has for decades been understood as playing a critical role in mood disorders and has more recently also been implicated in brain tumour biology. However, in part due to the lack… read more here.

Keywords: genetics; methylation; serotonin; maoa ... See more keywords

Yin Yang 1 (YY1)-induced long intergenic non-protein coding RNA 472 (LINC00472) aggravates sepsis-associated cardiac dysfunction via the micro-RNA-335-3p (miR-335-3p)/Monoamine oxidase A (MAOA) cascade

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recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2021.2017589

Abstract: ABSTRACT As a leading complication of sepsis, sepsis-induced cardiac dysfunction (SICD) contributed to the high mortality of patients with sepsis. Long non-coding RNA (LncRNA) LINC00472 has been reported to be in sepsis-induced disease. Nonetheless, its… read more here.

Keywords: yy1; cardiac dysfunction; mir 335; linc00472 ... See more keywords

Pilot study indicate role of preferentially transmitted monoamine oxidase gene variants in behavioral problems of male ADHD probands

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recommendations! Published in 2017 at "BMC Medical Genetics"

DOI: 10.1186/s12881-017-0469-5

Abstract: BackgroundAttention deficit hyperactivity disorder (ADHD) is an etiologically complex childhood onset neurobehavioral disorder characterized by age-inappropriate inattention, hyperactivity, and impulsivity. Symptom severity varies widely and boys are diagnosed more frequently than girls. ADHD probands were… read more here.

Keywords: maoa maob; etiology; adhd probands; monoamine oxidase ... See more keywords
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Single-Dose of Testosterone and the MAOA VNTR Polymorphism Influence Emotional and Behavioral Responses in Men During a Non-social Frustration Task

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recommendations! Published in 2020 at "Frontiers in Behavioral Neuroscience"

DOI: 10.3389/fnbeh.2020.00093

Abstract: Previous studies suggest that testosterone and several neurotransmitters might interactively influence human aggression. The current study aimed to test potential interactions of a genetic variation linked to the catabolism of serotonin, dopamine, and norepinephrine and… read more here.

Keywords: frustration task; non social; testosterone; maoa ... See more keywords

A synonymous mutation of rs1137070 cause the mice Maoa gene transcription and translation to decrease

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recommendations! Published in 2024 at "Frontiers in Molecular Neuroscience"

DOI: 10.3389/fnmol.2024.1406708

Abstract: The Monoamine Oxidase-A (MAOA) EcoRV polymorphism (rs1137070) is a unique synonymous mutation (c.1409 T > C) within the MAOA gene, which plays a crucial role in Maoa gene expression and function. This study aimed to explore the relationship… read more here.

Keywords: rs1137070; maoa; maoa gene; expression ... See more keywords

Interacting Effect of Catechol-O-Methyltransferase (COMT) and Monoamine Oxidase A (MAOA) Gene Polymorphisms, and Stressful Life Events on Aggressive Behavior in Chinese Male Adolescents

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recommendations! Published in 2018 at "Frontiers in Psychology"

DOI: 10.3389/fpsyg.2018.01079

Abstract: Numerous studies have demonstrated that both catechol-O-methyltransferase (COMT) gene and monoamine oxidase A (MAOA) gene have been involved in aggressive behavior, as have stressful life events (SLEs). However, most of available evidence was based upon… read more here.

Keywords: aggressive behavior; male adolescents; comt; maoa ... See more keywords

Combined Antagonism of 5-HT2 and NMDA Receptors Reduces the Aggression of Monoamine Oxidase a Knockout Mice

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recommendations! Published in 2022 at "Pharmaceuticals"

DOI: 10.3390/ph15020213

Abstract: The enzyme monoamine oxidase A (MAOA) catalyzes the degradation of several neurotransmitters, including serotonin. A large body of evidence has shown that genetic MAOA deficiency predisposes humans and mice to aggression and antisocial behavior. We… read more here.

Keywords: maoa; aggression; ket; reduces aggression ... See more keywords