A map of human individuality
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Genetics"
DOI: 10.1038/s41576-019-0149-8
Abstract: A study in Genome Biology reports an unbiased screen for human genomic regions at which interindividual variation in DNA methylation is consistent across cell types and tissues, providing new targets for studying epigenetic links to… read more here.
Keywords: map human; biology; human individuality;
Single-cell-resolution transcriptome map of human, chimpanzee, bonobo, and macaque brains.
Sign Up to like & getrecommendations! Published in 2020 at "Genome research"
DOI: 10.1101/gr.256958.119
Abstract: Identification of gene expression traits unique to the human brain sheds light on the molecular mechanisms underlying human evolution. Here we searched for uniquely human gene expression traits by analyzing 422 brain samples of humans,… read more here.
Keywords: single cell; transcriptome map; map human; cell ... See more keywords
Helicobacter pylori regulated microRNA map of human gastric cells
Sign Up to like & getrecommendations! Published in 2022 at "Helicobacter"
DOI: 10.1111/hel.12941
Abstract: Helicobacter pylori is an infection of concern for its chronic colonization leading to peptic ulcers and gastric cancer. In recent times, microRNAs have been extensively studied to understand their role in the pathogenesis of this… read more here.
Keywords: human gastric; map human; microrna map; regulated microrna ... See more keywords
47-OR: A Reference Map of the Human Proinsulin Biosynthetic Interaction Network
Sign Up to like & getrecommendations! Published in 2020 at "Diabetes"
DOI: 10.2337/db20-47-or
Abstract: The beta-cell protein synthetic machinery is dedicated to insulin production, and recent reports suggest misfolding of its precursor, proinsulin, is a feature of type 2 diabetes (T2D). Despite the critical role of insulin in organismal… read more here.
Keywords: interaction network; reference map; proinsulin; human proinsulin ... See more keywords