A microtubule-associated protein MAP1B binds to and regulates localization of a calcium-binding protein ALG-2.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.02.048
Abstract: MAP1B (microtubule-associated protein 1B) binds to microtubules and regulates microtubule dynamics. Previously, we showed calcium-dependent interaction between MAP1B and a calcium-binding protein ALG-2 (apoptosis-linked gene 2), which is involved in regulation of the protein secretion… read more here.
Keywords: alg; associated protein; map1b; microtubule associated ... See more keywords
MAP1B‐LC1 prevents autophagosome formation by linking syntaxin 17 to microtubules
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DOI: 10.15252/embr.201745584
Abstract: In fed cells, syntaxin 17 (Stx17) is associated with microtubules at the endoplasmic reticulum–mitochondria interface and promotes mitochondrial fission by determining the localization and function of the mitochondrial fission factor Drp1. Upon starvation, Stx17 dissociates… read more here.
Keywords: lc1 prevents; map1b; map1b lc1; autophagosome formation ... See more keywords
Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD–associated UBQLN2 mutants
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DOI: 10.26508/lsa.202101327
Abstract: Analysis of ALS patient-derived and engineered cells revealed that mutant UBQLN2 increases mRNA and protein of MAP1B which is mediated by dephosphorylation of FUS within its RNA-binding domain. Ubiquilin-2 (UBQLN2) is a ubiquitin-binding protein that… read more here.
Keywords: map1b; map1b axis; fus map1b; als ftd ... See more keywords