High-Throughput Functional Evaluation of MAP2K1 Variants in Cancer
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DOI: 10.1158/1535-7163.mct-22-0302
Abstract: Abstract Activating mutations in mitogen-activated protein kinase kinase 1 (MAP2K1) are involved in a variety of cancers and may be classified according to their RAF dependence. Sensitivity to combined BRAF and MEK treatments is associated… read more here.
Keywords: map2k1 variants; evaluation; sensitivity; braf ... See more keywords