Map3k8 controls granulocyte colony-stimulating factor production and neutrophil precursor proliferation in lipopolysaccharide-induced emergency granulopoiesis
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DOI: 10.1038/s41598-017-04538-3
Abstract: Map3k8 has been proposed as a useful target for the treatment of inflammatory diseases. We show here that during lipopolysaccharide-induced emergency granulopoiesis, Map3k8 deficiency strongly impairs the increase in circulating mature (Ly6GhighCD11b+) and immature (Ly6GlowCD11b+)… read more here.
Keywords: map3k8; emergency granulopoiesis; lipopolysaccharide induced; induced emergency ... See more keywords
Epigenetic Regulation of MAP3K8 in EBV-Associated Gastric Carcinoma
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DOI: 10.3390/ijms24031964
Abstract: Super-enhancers (SEs) regulate gene expressions, which are critical for cell type-identity and tumorigenesis. Although genome wide H3K27ac profiling have revealed the presence of SE-associated genes in gastric cancer (GC), their roles remain unclear. In this… read more here.
Keywords: ebvagc cells; gastric carcinoma; regulation map3k8; map3k8 ... See more keywords