Microtubule associated protein 4 (MAP4) phosphorylation reduces cardiac microvascular density through NLRP3-related pyroptosis
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DOI: 10.1038/s41420-021-00606-w
Abstract: Phosphorylation of MAP4 (p-MAP4) causes cardiac remodeling, with the cardiac microvascular endothelium being considered a vital mediator of this process. In the current study, we investigated the mechanism underlying p-MAP4 influences on cardiac microvascular density.… read more here.
Keywords: related pyroptosis; microvascular density; map4; nlrp3 related ... See more keywords
Microtubule-associated protein-4 controls nanovesicle dynamics and T cell activation
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DOI: 10.1242/jcs.199042
Abstract: ABSTRACT The immune synapse (IS) is a specialized structure formed at the contact area between T lymphocytes and antigen-presenting cells (APCs) that is essential for the adaptive immune response. Proper T cell activation requires its… read more here.
Keywords: protein; microtubule; map4; cell activation ... See more keywords