High PI3K/mTOR and low MAPK/JNK activity results in decreased apoptosis and autophagy in nasal polyposis.
Sign Up to like & getrecommendations! Published in 2020 at "Brazilian journal of otorhinolaryngology"
DOI: 10.1016/j.bjorl.2019.12.005
Abstract: INTRODUCTION Nasal polyposis is a progressive inflammatory disease that reduces the quality of life. The role - of apoptotic and autophagic pathways in nasal polyposis pathogenesis is not yet clearly known. OBJECTIVE In this study… read more here.
Keywords: pi3k; nasal polyposis; mtor; polyposis ... See more keywords
Green tea-derived theabrownin suppresses human non-small cell lung carcinoma in xenograft model through activation of not only p53 signaling but also MAPK/JNK signaling pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2022.115167
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE According to the theory and practice of traditional Chinese medicine (TCM), the pathogenesis of lung carcinoma is associated with many syndromes, such as "sputum stasis", "cough", "lung fever", "lung toxin", and "hemoptysis", which… read more here.
Keywords: lung; green tea; p53; cell ... See more keywords
The Role of p38 MAPK, JNK, and ERK in Antibacterial Responses of Chilo suppressalis (Lepidoptera: Crambidae)
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Economic Entomology"
DOI: 10.1093/jee/tox126
Abstract: Abstract The mitogen-activated protein kinases (MAPKs) are conserved signal transduction pathways and broadly responsible for bacterial infection from yeast to mammals, and virus, fungi, and bacteria, specifically Bacillus thuringiensis, to insects. But little is known… read more here.
Keywords: p38 mapk; role p38; chilo suppressalis; responses chilo ... See more keywords
Calcium phytate reverses high glucose-inhibited osteogenesis of BMSCs via the MAPK/JNK pathway.
Sign Up to like & getrecommendations! Published in 2023 at "Oral diseases"
DOI: 10.1111/odi.14598
Abstract: OBJECTIVES Diabetes mellitus (DM) induces oxidative tissue impairment and suppresses bone formation. Some studies have shown that phytic acid has antioxidant and anti-diabetic properties. This study aimed to investigate the potential of calcium phytate (Ca-phytate)… read more here.
Keywords: inhibited osteogenesis; jnk pathway; jnk; mapk jnk ... See more keywords
The Role of G3BP1 Gene Mediates P38 MAPK/JNK Pathway in Testicular Spermatogenic Dysfunction Caused by Cyfluthrin
Sign Up to like & getrecommendations! Published in 2023 at "Toxics"
DOI: 10.3390/toxics11050451
Abstract: In recent years, male infertility has received global attention and seriously affected the quality of human fertility, and pyrethroids (type II pyrethroids), as recognized environmental endocrine disruptors, may threaten male reproductive health. Therefore, in this… read more here.
Keywords: expression; jnk pathway; mapk jnk; p38 mapk ... See more keywords