MAPK7 variants related to prognosis and chemotherapy response in osteosarcoma.
Sign Up to like & getrecommendations! Published in 2020 at "Annals of diagnostic pathology"
DOI: 10.1016/j.anndiagpath.2020.151482
Abstract: Osteosarcoma (OS) is a class of cancer originating from the bone, affecting mainly children and young adults. Our previous study showed that MAPK7 gene overexpression was significantly associated with tumor progression, poor treatment response, and… read more here.
Keywords: chemotherapy; mapk7; response; variants related ... See more keywords
Mutant MAPK7-Induced Idiopathic Scoliosis is Linked to Impaired Osteogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000491956
Abstract: Background/Aims: Three rare MAPK7 variants that predispose individuals to adolescent idiopathic scoliosis have previously been identified. However, the mechanism underlying the effects of the mutations remain unknown. Methods: Human mesenchymal stem cells (hMSCs) were isolated… read more here.
Keywords: mapk7; idiopathic scoliosis; zebrafish embryos; impaired osteogenesis ... See more keywords