Cross-reactivities of mammalian MAPKs antibodies in rotifer and copepod: Application in mechanistic studies in aquatic ecotoxicology.
Sign Up to like & getrecommendations! Published in 2017 at "Marine pollution bulletin"
DOI: 10.1016/j.marpolbul.2016.11.049
Abstract: The mitogen-activated protein kinases (MAPKs) family is known to mediate various biological processes in response to diverse environmental pollutants. Although MAPKs are well characterized and studied in vertebrates, in invertebrates the cross-reactivities of MAPKs antibodies… read more here.
Keywords: cross reactivities; rotifer copepod; mapks antibodies; antibodies rotifer ... See more keywords
Ginsenoside Rg1 exerts neuroprotective effects in 3-nitropronpionic acid-induced mouse model of Huntington's disease via suppressing MAPKs and NF-κB pathways in the striatum.
Sign Up to like & getrecommendations! Published in 2020 at "Acta pharmacologica Sinica"
DOI: 10.1038/s41401-020-00558-4
Abstract: Huntington's disease (HD) is one of main neurodegenerative diseases, characterized by striatal atrophy, involuntary movements, and motor incoordination. Ginsenoside Rg1 (Rg1), an active ingredient in ginseng, possesses a variety of neuroprotective effects with low toxicity… read more here.
Keywords: neuroprotective effects; rg1; huntington disease; mapks ... See more keywords
Aesculetin exhibited anti-inflammatory activities through inhibiting NF-кB and MAPKs pathway in vitro and in vivo.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of ethnopharmacology"
DOI: 10.2139/ssrn.4019139
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Aesculetin (6,7-dihydroxy-2H-1-benzopyran-2-one) has been reported to exhibit potent anti-inflammatory property both in vitro and in vivo. AIMS OF THIS STUDY In this study, we evaluated the anti-inflammatory effect and investigated underlying molecular mechanisms… read more here.
Keywords: vitro vivo; aesculetin; dss induced; mapks ... See more keywords
Andrographolide Protects against Aortic Banding-Induced Experimental Cardiac Hypertrophy by Inhibiting MAPKs Signaling
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2017.00808
Abstract: Despite therapeutic advances, heart failure-related mortality rates remain high. Therefore, understanding the pathophysiological mechanisms involved in the remodeling process is crucial for the development of new therapeutic strategies. Andrographolide (Andr), a botanical compound, has potent… read more here.
Keywords: cardiac hypertrophy; aortic banding; mapks; experimental cardiac ... See more keywords
Impact of Conventional and Atypical MAPKs on the Development of Metabolic Diseases
Sign Up to like & getrecommendations! Published in 2020 at "Biomolecules"
DOI: 10.3390/biom10091256
Abstract: The family of mitogen-activated protein kinases (MAPKs) consists of fourteen members and has been implicated in regulation of virtually all cellular processes. MAPKs are divided into two groups, conventional and atypical MAPKs. Conventional MAPKs are… read more here.
Keywords: atypical mapks; kinase; family; mapks ... See more keywords
Regulation of Cortico-Thalamic JNK1/2 and ERK1/2 MAPKs and Apoptosis-Related Signaling Pathways in PDYN Gene-Deficient Mice Following Acute and Chronic Mild Stress
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032303
Abstract: The crosstalk between the opioidergic system and mitogen-activated protein kinases (MAPKs) has a critical role in mediating stress-induced behaviors related to the pathophysiology of anxiety. The present study evaluated the basal status and stress-induced alterations… read more here.
Keywords: stress; pdyn gene; mapks; cortico thalamic ... See more keywords
Chondroprotective Effects of Ulva prolifera on Osteoarthritis through MAPKs Signaling Inhibition
Sign Up to like & getrecommendations! Published in 2023 at "Preventive Nutrition and Food Science"
DOI: 10.3746/pnf.2023.28.1.43
Abstract: Osteoarthritis (OA) is a typical degenerative disease that mainly appears in the elderly aged 65 and over. OA is characterized by inflammation and decomposition of the cartilage matrix due to irreversible wear and tear. Ulva… read more here.
Keywords: mapks; ulva prolifera; prolifera; mmp mmp ... See more keywords