Articles with "mapl" as a keyword



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A new functional role of mitochondria-anchored protein ligase in peroxisome morphology in mammalian cells.

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Published in 2021 at "Journal of cellular biochemistry"

DOI: 10.1002/jcb.30114

Abstract: Mitochondria and peroxisomes are metabolically interconnected and functionally active subcellular organelles. These two dynamic organelles, share a number of common biochemical functions such as β-oxidation of fatty acids and detoxification of peroxides. The biogenesis and… read more here.

Keywords: mapl; fission; mitochondria anchored; morphology ... See more keywords

Deletion of MAPL ameliorates septic cardiomyopathy by mitigating mitochondrial dysfunction

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Published in 2024 at "Journal of Translational Medicine"

DOI: 10.1186/s12967-024-05836-x

Abstract: Mitochondrial dysfunction is a critical factor in the pathogenesis of septic cardiomyopathy (SCM). Mitochondrial anchored protein ligase (MAPL), a small ubiquitin-like modifier (SUMO) E3 ligase, plays a significant role in mitochondrial function. However, the role… read more here.

Keywords: mapl; dysfunction; mitochondrial dysfunction; heart tissues ... See more keywords