Mapping benznidazole resistance in trypanosomatids and exploring evolutionary histories of Nitroreductases and ABCG transporter protein sequences.
Sign Up to like & getrecommendations! Published in 2019 at "Acta tropica"
DOI: 10.1016/j.actatropica.2019.105161
Abstract: The nitro-heterocyclic compound benznidazole (BZ) is the first-line drug for the treatment of Chagas disease, caused by the protozoan Trypanosoma cruzi. However, therapeutic failures are common for reasons that include the influences of parasite and… read more here.
Keywords: benznidazole resistance; trypanosoma species; resistance trypanosomatids; mapping benznidazole ... See more keywords