Mapping pH at Cancer Cell Surfaces
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Imaging and Biology"
DOI: 10.1007/s11307-019-01335-4
Abstract: PurposeTo develop a tool to measure the pH at the surfaces of individual cells.ProceduresThe SNARF pH-sensitive dye was conjugated to a pHLIP® peptide (pH-Low Insertion Peptide) that binds cellular membranes in tumor spheroids. A beam… read more here.
Keywords: cell surfaces; glycolytic activity; mapping cancer; cancer cell ... See more keywords
Mapping cancer genetics at single-cell resolution
Sign Up to like & getrecommendations! Published in 2020 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.abd3049
Abstract: CRISPR genetic interaction mapping reveals networks of genes that drive cancer phenotypes. CRISPR genetic interaction mapping reveals networks of genes that drive cancer phenotypes. read more here.
Keywords: single cell; genetics; mapping cancer; genetics single ... See more keywords