A Lanthanide Upconversion Nanothermometer for Precise Temperature Mapping on Immune Cell Membrane.
Sign Up to like & getrecommendations! Published in 2022 at "Nano letters"
DOI: 10.1021/acs.nanolett.2c03392
Abstract: Cell temperature monitoring is of great importance to uncover temperature-dependent intracellular events and regulate cellular functions. However, it remains a great challenge to precisely probe the localized temperature status in living cells. Herein, we report… read more here.
Keywords: temperature; mapping immune; cell membrane; temperature mapping ... See more keywords
Mapping the Immune Landscape in Metastatic Melanoma Reveals Localized Cell–Cell Interactions That Predict Immunotherapy Response
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Research"
DOI: 10.1158/0008-5472.can-22-0363
Abstract: This study shows that spatial characterization can address the challenge of finding efficient biomarkers, revealing that localization of macrophages and T cells in melanoma predicts patient response to ICI. read more here.
Keywords: cell; landscape metastatic; mapping immune; immune landscape ... See more keywords
Abstract 2070: Subcellular mapping of immune repertoire profiles with in situ sequencing on G4X
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-2070
Abstract: Detailed spatial analysis of immunology and pathology, such as immune repertoire profiling in tissue, requires in situ sequencing of variable gene regions. We introduce Direct-Seq, a novel technology using the G4X platform for in situ… read more here.
Keywords: immune repertoire; mapping immune; repertoire profiles; situ sequencing ... See more keywords