Mapping proteomic signatures in iPSC-derived neutrophils: Modeling neutropenia
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DOI: 10.1182/blood-2025-1212
Abstract: Severe congenital neutropenia (SCN) encompasses a diverse range of genetic defects that impair the differentiation and function of neutrophil granulocytes. Our study aims to characterize proteomic differences in distinct developmental stages of neutrophils with pathogenic… read more here.
Keywords: differentiation; maturation stages; mapping proteomic; derived neutrophils ... See more keywords