Mapping Tumor-Specific Expression QTLs in Impure Tumor Samples
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Statistical Association"
DOI: 10.1080/01621459.2019.1609968
Abstract: Abstract The study of gene expression quantitative trait loci (eQTL) is an effective approach to illuminate the functional roles of genetic variants. Computational methods have been developed for eQTL mapping using gene expression data from… read more here.
Keywords: normal cells; tumor samples; specific expression; expression ... See more keywords
Abstract PD5-07: Mapping the tumor and microenvironmental evolution underlying DCIS progression throughmultiplexed ion beam imaging
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs20-pd5-07
Abstract: Ductal Carcinoma in Situ (DCIS) is a pre-invasive lesion that accounts for nearly 20% of new breast cancer diagnoses. Of these cases, about half will progress to invasive breast cancer (IBC) within ten years. However,… read more here.
Keywords: beam imaging; ion beam; mapping tumor; tumor ... See more keywords
Advances in Mapping Tumor Progression from Precancer Atlases.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer prevention research"
DOI: 10.1158/1940-6207.capr-22-0473
Abstract: Tissue profiling technologies present opportunities for understanding transition from precancerous lesions to malignancy, which may impact risk stratification, prevention, and even cancer treatment. A human precancer atlas (PCA) building effort is ongoing to tackle the… read more here.
Keywords: tumor progression; progression; mapping tumor; progression precancer ... See more keywords
Mapping the Tumor Microenvironment in TNBC and Deep Exploration for M1 Macrophages-Associated Prognostic Genes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.923481
Abstract: Triple negative breast cancer (TNBC) remains the worst molecular subtype due to high heterogeneity and lack of effective therapeutic targets. Here we investigated the tumor and immune microenvironment heterogeneity of TNBC using scRNA-seq and bulk… read more here.
Keywords: macrophages associated; mapping tumor; tumor microenvironment; tnbc ... See more keywords