Conserved gene signatures shared among MAPT mutations reveal defects in calcium signaling
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DOI: 10.3389/fmolb.2023.1051494
Abstract: Introduction: More than 50 mutations in the MAPT gene result in heterogeneous forms of frontotemporal lobar dementia with tau inclusions (FTLD-Tau). However, early pathogenic events that lead to disease and the degree to which they… read more here.
Keywords: calcium; differentially expressed; mapt mutations; conserved gene ... See more keywords