Effect of supportive therapy on the pharmacokinetics of intravenous marbofloxacin in endotoxemic sheep.
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DOI: 10.1111/jvp.12849
Abstract: The purpose of this study was to determine the influences of supportive therapy (ST) on the pharmacokinetics (PK) of marbofloxacin in lipopolysaccharide (LPS)-induced endotoxemic sheep. Furthermore, minimum inhibitory concentration (MIC) of marbofloxacin against Escherichia coli,… read more here.
Keywords: supportive therapy; therapy pharmacokinetics; endotoxemic sheep; marbofloxacin ... See more keywords
Pharmacokinetic / Pharmacodynamic Evaluation of Marbofloxacin for Common Pathogens in Swine Following Single Intramuscular Administration of Different Doses
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DOI: 10.29261/pakvetj/2018.046
Abstract: Received: Revised: Accepted: Published online: September 12, 2017 November 25, 2017 January 10, 2018 April 17, 2018 The aims of the present work were to study the pharmacokinetics of marbofloxacin 10% solution after single i.m.… read more here.
Keywords: administration; common pathogens; pharmacokinetic pharmacodynamic; pharmacodynamic evaluation ... See more keywords
Pharmacokinetic and Pharmacodynamic Evaluation of Marbofloxacin and PK/PD Modeling against Escherichia coli in Pigs
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DOI: 10.3389/fphar.2017.00542
Abstract: The aim of this study was to evaluate the activity of marbofloxacin and establish the optimal dose regimens for decreasing the development of fluoroquinolone resistance in pigs against Escherichia coli with ex vivo pharmacokinetic/pharmacodynamic (PK/PD)… read more here.
Keywords: ileum content; escherichia coli; coli; pharmacokinetic pharmacodynamic ... See more keywords
PK-PD Analysis of Marbofloxacin against Streptococcus suis in Pigs
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DOI: 10.3389/fphar.2017.00856
Abstract: Marbofloxacin is a fluoroquinolone antibiotic and highly effective treatment for respiratory diseases. Here we aimed to evaluate the ex vivo activity of marbofloxacin against Streptococcus suis in pig serum, as well as the optimal dosages… read more here.
Keywords: marbofloxacin streptococcus; streptococcus suis; serum; marbofloxacin ... See more keywords
Tissue distribution of marbofloxacin in pigs after a single intramuscular injection
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DOI: 10.4142/jvs.2017.18.2.169
Abstract: Tissue distribution of marbofloxacin was studied in pigs after a single intramuscular injection at 2.5 mg/kg body weight. Samples of plasma, muscle, liver, kidney, heart, lung, and muscle at the injection site were randomly collected… read more here.
Keywords: single intramuscular; tissue distribution; muscle; pigs single ... See more keywords