Short survival and frequent transformation in extranodal marginal zone lymphoma with multiple mucosal sites presentation
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Hematology"
DOI: 10.1002/ajh.25446
Abstract: Between 11 and 37% of extranodal marginal zone lymphoma (EMZL) patients present with disease involvement in multiple mucosal sites (MMS). We analyzed 405 EMZL patients seen between 1995 and 2017: 265 (65.4%) patients presented with… read more here.
Keywords: marginal zone; presentation; zone lymphoma; extranodal marginal ... See more keywords
Long‐term outcomes of patients with conjunctival extranodal marginal zone lymphoma
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DOI: 10.1002/ajh.26591
Abstract: Comprehensive information on clinical features and long‐term outcomes of primary conjunctival extranodal marginal zone lymphoma (PCEMZL) is scarce. We present a large single‐institution retrospective study of 72 patients. The median age was 64 years, and 63.9%… read more here.
Keywords: long term; term outcomes; term; extranodal marginal ... See more keywords
A roadmap for clinical trial design in marginal zone lymphoma
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26706
Abstract: Significant advances in the drug development of indolent non-Hodg-kin lymphoma (iNHL) occurred over the last years expanding the landscape of treatment options. Several novel agents have been approved by the US Food and Drug Administration… read more here.
Keywords: lymphoma; design marginal; roadmap clinical; clinical trial ... See more keywords
Time trends and survival of marginal zone lymphoma over 25 years in Girona, Spain (1994-2018).
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.5935
Abstract: OBJECTIVE To analyze the incidence, incidence trends, and survival of marginal zone lymphomas (MZLs) in Girona and to describe these indicators based on the location in the case of extranodal MZLs. METHODS Population-based study of… read more here.
Keywords: incidence; 100 000; survival marginal; mzl ... See more keywords
Splenic marginal zone lymphoma: A US population‐based survival analysis (1999‐2016)
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DOI: 10.1002/cncr.33117
Abstract: Splenic marginal zone lymphoma (SMZL) is a rare tumor without a uniform treatment approach. The authors describe a large population‐based study evaluating survival outcomes of patients with SMZL according to the treatment received. read more here.
Keywords: population based; splenic marginal; marginal zone; zone lymphoma ... See more keywords
A temporally resolved transcriptome for developing “Keller” explants of the Xenopus laevis dorsal marginal zone
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DOI: 10.1002/dvdy.289
Abstract: Explanted tissues from vertebrate embryos reliably develop in culture and have provided essential paradigms for understanding embryogenesis, from early embryological investigations of induction, to the extensive study of Xenopus animal caps, to the current studies… read more here.
Keywords: marginal zone; keller explants; explants xenopus; dorsal marginal ... See more keywords
FDG PET/CT as a diagnostic and prognostic tool for the evaluation of marginal zone lymphoma
Sign Up to like & getrecommendations! Published in 2019 at "Hematological Oncology"
DOI: 10.1002/hon.2578
Abstract: We evaluated the role of 18‐fluoro‐2‐deoxy‐d‐glucose positron emission tomography ([18F] FDG‐PET) with computed tomography (CT) (PET/CT) as a diagnostic and prognostic tool in newly diagnosed marginal zone lymphoma (MZL) patients. read more here.
Keywords: marginal zone; diagnostic prognostic; prognostic tool; pet diagnostic ... See more keywords
A phase II trial of bendamustine in combination with ofatumumab in patients with relapsed or refractory marginal zone B‐cell lymphomas
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DOI: 10.1002/hon.2822
Abstract: Marginal zone lymphomas (MZLs) are indolent yet incurable lymphomas with frequent relapses following therapy. For patients with relapsed/refractory disease, no standard therapies exist. Here we report results of an exploratory phase II study aimed at… read more here.
Keywords: relapsed refractory; marginal zone; trial; bendamustine combination ... See more keywords
Unmet clinical needs in the use of zanubrutinib in malignant lymphomas (Waldenström macroglobulinemia, marginal zone lymphoma and mantle cell lymphoma): A consensus-based position paper from an ad hoc expert panel.
Sign Up to like & getrecommendations! Published in 2023 at "Hematological oncology"
DOI: 10.1002/hon.3172
Abstract: Zanubrutinib has been approved for the treatment of patients with different lymphoproliferative disorders, and now represents a major breakthrough in the treatment of patients resistant or relapsing after the recommended therapies. Because few systematic studies… read more here.
Keywords: clinical needs; use zanubrutinib; zanubrutinib; unmet clinical ... See more keywords
Kindlin‐3 maintains marginal zone B cells but confines follicular B cell activation and differentiation
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DOI: 10.1002/jlb.1hi0621-313r
Abstract: Integrin‐mediated interactions between hematopoietic cells and their microenvironment are important for the development and function of immune cells. Here, the role of the integrin adaptor Kindlin‐3 in B cell homeostasis is studied. Comparing the individual… read more here.
Keywords: kindlin; follicular cell; cell; marginal zone ... See more keywords
Genetic alterations and their prognostic impact in marginal zone lymphoma: a meta-analysis
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DOI: 10.1007/s00277-024-06175-z
Abstract: This meta-analysis aimed to assess the impact of genetic mutations, particularly in the NOTCH2 and TNFAIP3 genes, on the prognostic outcomes of Marginal Zone Lymphoma (MZL) patients. Databases, including PubMed, Embase, and Cochrane Library, were… read more here.
Keywords: impact; meta analysis; marginal zone; zone lymphoma ... See more keywords