Saccharochelins A-H, Cytotoxic Amphiphilic Siderophores from the Rare Marine Actinomycete Saccharothrix sp. D09.
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DOI: 10.1021/acs.jnatprod.1c00155
Abstract: Siderophores are secreted by microorganisms to survive in iron-depleted conditions, and they also possess tremendous therapeutic potential. Genomic-inspired isolation facilitated the identification of eight amphiphilic siderophores, saccharochelins A-H (1-8), from a rare marine-derived Saccharothrix species.… read more here.
Keywords: cytotoxic amphiphilic; marine actinomycete; siderophores rare; saccharochelins cytotoxic ... See more keywords
Targeted Discovery of an Enediyne-Derived Cycloaromatized Compound, Jejucarboside A, from a Marine Actinomycete.
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DOI: 10.1021/acs.orglett.2c02934
Abstract: A genomic and spectroscopic signature-based search revealed a cycloaromatized enediyne, jejucarboside A (1), from a marine actinomycete strain. The structure of 1 was determined as a new cyclopenta[a]indene glycoside bearing carbonate functionality by nuclear magnetic… read more here.
Keywords: enediyne; discovery enediyne; jejucarboside marine; marine actinomycete ... See more keywords
Amycolachromones A–F, Isolated from a Streptomycin-Resistant Strain of the Deep-Sea Marine Actinomycete Amycolatopsis sp. WP1
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DOI: 10.3390/md20030162
Abstract: In this study, a detailed chemical investigation of a streptomycin-resistant strain of the deep-sea marine, actinomycete Amycolatopsis sp. WP1, yielded six novel amycolachromones A–F (1–6), together with five known analogues (7–11). Amycolachromones A–B (1–2) possessed… read more here.
Keywords: deep sea; sea marine; streptomycin resistant; resistant strain ... See more keywords