Study of Structure–Activity Relationships of the Marine Alkaloid Fascaplysin and Its Derivatives as Potent Anticancer Agents
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DOI: 10.3390/md20030185
Abstract: Marine alkaloid fascaplysin and its derivatives are known to exhibit promising anticancer properties in vitro and in vivo. However, toxicity of these molecules to non-cancer cells was identified as a main limitation for their clinical… read more here.
Keywords: structure activity; alkaloid fascaplysin; fascaplysin derivatives; activity ... See more keywords
Unique Mode of Antiviral Action of a Marine Alkaloid against Ebola Virus and SARS-CoV-2
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DOI: 10.3390/v14040816
Abstract: Lamellarin α 20-sulfate is a cell-impenetrable marine alkaloid that can suppress infection that is mediated by the envelope glycoprotein of human immunodeficiency virus type 1. We explored the antiviral action and mechanisms of this alkaloid… read more here.
Keywords: alkaloid; ebola virus; action; marine alkaloid ... See more keywords