Synthesis of Marine Cyclopeptide Galaxamide Analogues as Potential Anticancer Agents
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DOI: 10.3390/md20030158
Abstract: In this paper, eight new galaxamide analogues (Z-1~Z-8) were synthesized and evaluated for their cytotoxic activities against five cancer cell lines, MCF-7, MD-MBA-231, HepG2, Hela, and A549, using MTT assays. The modified analogue Z-6 displayed… read more here.
Keywords: analogues potential; cyclopeptide galaxamide; galaxamide analogues; galaxamide ... See more keywords
Photoinduced Synthesis of Methylated Marine Cyclopeptide Galaxamide Analogs with Isoindolinone as Anticancer Agents
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DOI: 10.3390/md20060379
Abstract: The methylation of amino acid residues has played an important role in the biological function of bioactive peptides. In this paper, various methyl-modified and stereostructural-modified marine cyclopeptide galaxamide analogs with isoindolinone were synthesized by a… read more here.
Keywords: marine cyclopeptide; analogs isoindolinone; cyclopeptide galaxamide; galaxamide analogs ... See more keywords