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Published in 2018 at "Macromolecular bioscience"
DOI: 10.1002/mabi.201800137
Abstract: The control of biofouling, which is the unwanted adsorption of biomolecules and organisms on solid surfaces, is a prerequisite for wider applicability of the functional materials that are currently being used in biomedical industries. One…
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Keywords:
multipurpose antifouling;
fucoidan;
coating solid;
solid surfaces ... See more keywords
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Published in 2022 at "Small"
DOI: 10.1002/smll.202200416
Abstract: Prompt and robust bone regeneration has been clinically achieved using supraphysiological doses of bone morphogenetic protein-2 (BMP-2) to overcome the short half-life and rapid clearance. However, uncontrolled burst release of exogenous BMP-2 causes severe complications…
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Keywords:
superior bmp;
bmp binding;
bmp;
bone ... See more keywords
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Published in 2018 at "Medicinal Chemistry Research"
DOI: 10.1007/s00044-018-2201-1
Abstract: AbstractThe new halogenated metabolites cryptophomic acid (1), cryptodiol (2), and cryptotriol (3) and the known dihydro-isocoumarin derivative 4, were isolated from the marine-derived fungus Phoma sp.135. The structural elucidation of these compounds was achieved by…
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Keywords:
marine derived;
derived fungus;
new bioactive;
dihydro isocoumarin ... See more keywords
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Published in 2017 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-017-8707-5
Abstract: A highly enantioselective and minimally polluting approach to optically pure chiral alcohols is developed using cheap, readily available and sustainable marine-derived fungi as catalysts. An evaluation of the synthetic potential of 13 Chinese marine fungi…
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Keywords:
preparation enantiomerically;
enantiomerically pure;
derived fungi;
use marine ... See more keywords
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Published in 2018 at "3 Biotech"
DOI: 10.1007/s13205-018-1307-y
Abstract: Peptide mass fingerprinting of Gram-positive marine-derived Staphylococcus cohnii #NIOSBK35 gave us an insight into the proteins involved in conferring arsenic resistance as well as the probable metabolic pathways affected under metal stress. Analysis of the…
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Keywords:
protein;
metabolism;
derived staphylococcus;
time ... See more keywords
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Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.105111
Abstract: Furanaspermeroterpenes A (1) and B (2), with a unique 6/6/6/5/5 pentacyclic skeleton, and five new congeners aspermeroterpenes D-H (3-7) were co-isolated from the marine-derived fungus Aspergillus terreus GZU-31-1. Among them, compounds 1 and 2 with…
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Keywords:
unique pentacyclic;
derived fungus;
pentacyclic skeleton;
fungus aspergillus ... See more keywords
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Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.105375
Abstract: A new diphenylamine derivative, scediphenylamine A (1), together with six phthalimide derivatives (2-7) and ten other known compounds (8-17) were obtained from the marine-derived fungus Scedosporium apiospermum F41-1 fed with synthetically prepared anthranilic acid and…
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Keywords:
derived fungus;
scedosporium apiospermum;
apiospermum f41;
anthranilic acid ... See more keywords
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Published in 2021 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2020.111619
Abstract: Fluorene, a low molecular weight polycyclic aromatic hydrocarbon (PAH), is of immense environmental interest because of its carcinogenicity, teratogenicity, mutagenicity, toxicity and persistence to microbial degradation. Existentially, there is paucity of information on PAH degradation…
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Keywords:
degradation;
methodology;
isolated marine;
fluorene degradation ... See more keywords
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Published in 2019 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2019.05.025
Abstract: Abstract (±)-Eurotone A [(±)- 1 ], a pair of new enantiomeric polyketide dimers, as well as six known biogenetically related polyketides ( 2 – 7 ) were isolated from a marine-derived fungus Eurotium sp. SCSIO…
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Keywords:
enantiomeric polyketide;
eurotone pair;
derived fungus;
polyketide dimers ... See more keywords
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Published in 2021 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c00175
Abstract: Reported as two antirenal cell carcinoma (RCC) drug candidates, marine-derived compounds piericidin A (PA) and glucopiericidin A (GPA) exhibit hepatotoxicity in renal carcinoma xenograft mice. Proteomics and transcriptomics reveal the hepatotoxicity related with cholesterol disposition…
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Keywords:
lxr;
cholesterol;
mice;
cholesterol diet ... See more keywords
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Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c01989.s001
Abstract: Upregulation of ATP binding cassette (ABC) transporter efflux pumps (i.e. P-glycoprotein, P-gp) can impart multidrug resistance, rendering many chemotherapeutics ineffective and seriously limiting treatment regimes. While ABC transporters remain an attractive target for therapeutic intervention,…
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Keywords:
directed biosynthesis;
inhibitory pharmacophore;
precursor directed;
marine derived ... See more keywords