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Published in 2022 at "Analytical Chemistry"
DOI: 10.1021/acs.analchem.2c02185
Abstract: Dinoflagellate-derived polyketides are typically large molecules (>1000 Da) with complex structures, potent bioactivities, and high toxicities. Their discovery suffers three major bottlenecks: insufficient bioavailability, low-yield cultivation of producer organisms, and production of multiple highly related…
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Keywords:
screening polyol;
polyol polyketides;
polyketides marine;
polyol ... See more keywords
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3
Published in 2022 at "Marine Drugs"
DOI: 10.3390/md20040253
Abstract: This paper examined the toxins naturally produced by marine dinoflagellates and their effects on increases in β-amyloid plaques along with tau protein hyperphosphorylation, both major drivers of Alzheimer’s disease (AD). This approach is in line…
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Keywords:
disease toxins;
produced marine;
toxins produced;
alzheimer disease ... See more keywords