Discovery of a Phenylamine-Incorporated Angucyclinone from Marine Streptomyces sp. PKU-MA00218 and Generation of Derivatives with Phenylamine Analogues.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b00800
Abstract: A new phenylamine-incorporated angucyclinone (1) featuring a unique 1-phenylbenzo[ cd]indol-3(1 H)-one moiety was discovered from marine Streptomyces sp. PKU-MA00218. A series of experimental investigations identified that 1 was produced from the nonenzymatic conversion of a… read more here.
Keywords: phenylamine incorporated; pku ma00218; phenylamine; streptomyces pku ... See more keywords
Marine Streptomyces sp. derived antimycin analogues suppress HeLa cells via depletion HPV E6/E7 mediated by ROS-dependent ubiquitin–proteasome system
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DOI: 10.1038/srep42180
Abstract: Four new antimycin alkaloids (1–4) and six related known analogs (5–10) were isolated from the culture of a marine derived Streptomyces sp. THS-55, and their structures were elucidated by extensive spectroscopic analysis. All of the… read more here.
Keywords: proteasome system; streptomyces derived; hpv; marine streptomyces ... See more keywords
A new δ-valerolactone produced by marine Streptomyces sp. YIM 13591.
Sign Up to like & getrecommendations! Published in 2022 at "Natural product research"
DOI: 10.1080/14786419.2022.2030734
Abstract: A new δ-valerolactone compound, named 8-hydroxy invictolide 2 (1), a new natural product 4-hydroxy-3,5-dimethyl-6-(pentan-2-yl) tetrahydro-2H-pyran-2-one (2) together with four known compounds cyclo (L-Pro-L-Tyr) (3), cyclo (D-Pro-L-Tyr) (4), acetyltryptophan methyl ester (5), 2-aminobenzoic acid (6) were… read more here.
Keywords: new valerolactone; yim 13591; valerolactone produced; streptomyces yim ... See more keywords
Metabolomic study of marine Streptomyces sp.: Secondary metabolites and the production of potential anticancer compounds
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DOI: 10.1371/journal.pone.0244385
Abstract: Resorting to a One Strain Many Compounds (OSMAC) approach, the marine Streptomyces sp. BRB081 strain was grown in six different media settings over 1, 2, 3 or 7 days. Extractions of mycelium and broth were… read more here.
Keywords: production; data treatment; marine streptomyces; crude extracts ... See more keywords
Marine Streptomyces sp. VITASP as a Source of New Bioactive Secondary Metabolites
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DOI: 10.2174/1573407214666180904100049
Abstract: The main aim of the study was to evaluate the bioactive properties of ethyl acetate crude extract of Streptomyces sp. VITASP with a view to assess their therapeutic potential. The morphological, physiological and the biochemical… read more here.
Keywords: source; new bioactive; streptomyces vitasp; marine streptomyces ... See more keywords
Coculture of Marine Streptomyces sp. With Bacillus sp. Produces a New Piperazic Acid-Bearing Cyclic Peptide
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2018.00498
Abstract: Microbial culture conditions in the laboratory, which conventionally involve the cultivation of one strain in one culture vessel, are vastly different from natural microbial environments. Even though perfectly mimicking natural microbial interactions is virtually impossible,… read more here.
Keywords: cyclic peptide; marine streptomyces; dentigerumycin; coculture marine ... See more keywords
Overexpression and Biochemical Properties of a GH46 Chitosanase From Marine Streptomyces hygroscopicus R1 Suitable for Chitosan Oligosaccharides Preparation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.816845
Abstract: Due to the various biological activities of chitosan oligosaccharides (COSs), they have great potential value for use in many areas. Chitosanase plays an important role in enzymatic preparation of COSs. Herein, a gene encoding a… read more here.
Keywords: marine streptomyces; chitosan oligosaccharides; streptomyces hygroscopicus; chitosanase ... See more keywords
Acyl Chain Specificity of Marine Streptomyces klenkii PhosPholipase D and Its Application in Enzymatic Preparation of Phosphatidylserine
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DOI: 10.3390/ijms221910580
Abstract: Mining of phospholipase D (PLD) with altered acyl group recognition except its head group specificity is also useful in terms of specific acyl size phospholipid production and as diagnostic reagents for quantifying specific phospholipid species.… read more here.
Keywords: chain; marine streptomyces; acyl chain; streptomyces klenkii ... See more keywords
SNA077, an Extract of Marine Streptomyces sp., Inhibits Melanogenesis by Downregulating Melanogenic Proteins via Inactivation of cAMP/PKA/CREB Signaling
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232314922
Abstract: Excess melanin in skin is known to be the main cause of hyper-pigmentary skin diseases such as freckles and lentigo. This study aimed to evaluate the depigmenting efficacy of an extract from the marine microorganism… read more here.
Keywords: marine streptomyces; sna077; pka; expression ... See more keywords
Stress-Driven Discovery of New Angucycline-Type Antibiotics from a Marine Streptomyces pratensis NA-ZhouS1
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DOI: 10.3390/md16090331
Abstract: Natural products from marine actinomycetes remain an important resource for drug discovery, many of which are produced by the genus, Streptomyces. However, in standard laboratory conditions, specific gene clusters in microbes have long been considered… read more here.
Keywords: antibiotics marine; marine streptomyces; stress; new angucycline ... See more keywords