Mycobacterium marinum: a rare cause of chronic lymphocutaneous syndrome
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pediatrics"
DOI: 10.1007/s00431-018-3102-5
Abstract: We investigated the prevalence of Mycobacterium marinum lymphadenitis and describe 4 children with the disease. The database of the microbiology laboratory of a tertiary pediatric medical center was searched for all cases of nontuberculous mycobacterial… read more here.
Keywords: mycobacterium marinum; cause chronic; lymphocutaneous syndrome; lymphadenitis ... See more keywords
Structural analysis and functional study of phosphofructokinase B (PfkB) from Mycobacterium marinum.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.09.051
Abstract: Phosphofructokinase B (PfkB) belongs to the ribokinase family, which uses the phosphorylated sugar as substrate, and catalyzes fructose-6-phosphate into fructose-1,6-diphosphate. However, the structural basis of Mycobacterium marinum PfkB is not clear. Here, we found that… read more here.
Keywords: marinum; mycobacterium marinum; pfkb; phosphofructokinase pfkb ... See more keywords
Eosinophilic Leukaemia and Systemic Mycobacterium marinum Infection in an African Pygmy Hedgehog (Atelerix albiventris).
Sign Up to like & getrecommendations! Published in 2020 at "Journal of comparative pathology"
DOI: 10.1016/j.jcpa.2020.09.013
Abstract: A two-year-old male African pygmy hedgehog (Atelerix albiventris) presented with lethargy and anorexia. Ultrasonographic and radiographic examinations revealed splenomegaly and pneumonia, respectively. Prominent leucocytosis, consisting mainly of large atypical eosinophils, was observed in a peripheral blood… read more here.
Keywords: pygmy hedgehog; mycobacterium marinum; hedgehog atelerix; marinum ... See more keywords
DNA vaccination with the Mycobacterium marinum MMAR_4110 antigen inhibits reactivation of a latent mycobacterial infection in the adult Zebrafish.
Sign Up to like & getrecommendations! Published in 2020 at "Vaccine"
DOI: 10.1016/j.vaccine.2020.06.053
Abstract: BACKGROUND Tuberculosis is a major challenge for health care, as options for its treatment and prevention are limited. Therefore, novel approaches, such as DNA vaccination, to both prevent primary infections and the reactivation of latent… read more here.
Keywords: mmar; infection; reactivation latent; reactivation ... See more keywords
WhiB4 Regulates the PE/PPE Gene Family and is Essential for Virulence of Mycobacterium marinum
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-03020-4
Abstract: During the course of infection, pathogenic mycobacteria including Mycobacterium tuberculosis (M. tb) encounter host environments of variable oxygen tension, ranging from the hypoxic center of granulomas to the most oxygenated region in the lung cavities.… read more here.
Keywords: whib4; mycobacterium marinum; virulence; marinum whib4 ... See more keywords
Mycobacterium marinum infections in Denmark from 2004 to 2017: A retrospective study of incidence, patient characteristics, treatment regimens and outcome
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-24702-7
Abstract: Mycobacterium marinum (M. marinum) is a slowly growing nontuberculous mycobacterium. The incidence of M. marinum infections in Denmark is unknown. We conducted a retrospective nationwide study including all culture confirmed cases of M. marinum from… read more here.
Keywords: mycobacterium marinum; treatment; marinum infections; marinum ... See more keywords
Genital mycobacteriosis caused by Mycobacterium marinum detected in two captive sharks by peptide nucleic acid–fluorescence in situ hybridization
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Fish Diseases"
DOI: 10.1111/jfd.13716
Abstract: Abstract Mycobacterium marinum is a prevalent nontuberculous mycobacterium (NTM)‐infecting teleosts. Conversely, little is known about mycobacteriosis in elasmobranchs, and M. marinum infection has never been reported from the subclass. This study investigated the histopathological characteristics… read more here.
Keywords: marinum; captive sharks; mycobacterium; two captive ... See more keywords
PPE Barcoding Identifies Biclonal Mycobacterium ulcerans Buruli Ulcer, Côte d’Ivoire
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00342-23
Abstract: We describe a new targeted sequencing approach that characterizes the PPE gene to disclose the simultaneous presence of different variants of a single pathogenic microorganism. This approach has direct implications on the understanding of pathogen… read more here.
Keywords: marinum; marinum ulcerans; ppe gene; mycobacterium ... See more keywords
WhiB4 Is Required for the Reactivation of Persistent Infection of Mycobacterium marinum in Zebrafish
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00443-21
Abstract: About one-quarter of the world’s population has latent TB infection, and 5 to 10% of those individuals will fall ill with TB. Our finding suggests that WhiB4 is an attractive target for the development of… read more here.
Keywords: marinum; infection; reactivation; latent infection ... See more keywords
Rational design of drug-like compounds targeting Mycobacterium marinum MelF protein
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0183060
Abstract: The mycobacterial mel2 locus (mycobacterial enhanced infection locus, Rv1936-1941) is Mycobacterium marinum and M. tuberculosis specific, which can withstand reactive oxygen species (ROS) and reactive nitrogen species (RNS) induced stress. A library of over a… read more here.
Keywords: mycobacterium marinum; marinum; melf protein; marinum melf ... See more keywords
Mycobacterium marinum antagonistically induces an autophagic response while repressing the autophagic flux in a TORC1- and ESX-1-dependent manner
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1006344
Abstract: Autophagy is a eukaryotic catabolic process also participating in cell-autonomous defence. Infected host cells generate double-membrane autophagosomes that mature in autolysosomes to engulf, kill and digest cytoplasmic pathogens. However, several bacteria subvert autophagy and benefit… read more here.
Keywords: mycobacterium marinum; esx dependent; autophagic flux; autophagic response ... See more keywords