Histone mark recognition controls nucleosome translocation via a kinetic proofreading mechanism: Confronting theory and high-throughput experiments.
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DOI: 10.1103/physreve.99.060401
Abstract: Chromatin remodelers are multidomain enzymatic motor complexes that displace nucleosomes along DNA and hence "remodel chromatin structure," i.e., they dynamically reorganize nucleosome positions in both gene activation and gene repression. Recently, experimental insights from structural… read more here.
Keywords: chromatin; mark recognition; histone mark; kinetic proofreading ... See more keywords