Marked reduction in paralytic attacks in a patient with Andersen-Tawil syndrome switched from acetazolamide to dichlorphenamide
Sign Up to like & getrecommendations! Published in 2021 at "Neuromuscular Disorders"
DOI: 10.1016/j.nmd.2021.04.001
Abstract: Andersen-Tawil syndrome is a rare, autosomal dominant, multisystem disorder for which the majority of cases are caused by pathogenic variants in the KCNJ2 gene. The syndrome is characterized by the clinical triad of episodic paralysis,… read more here.
Keywords: andersen tawil; marked reduction; paralytic attacks; tawil syndrome ... See more keywords
Soluble Guanylate Cyclase β1 Subunit Represses Human Glioblastoma Growth
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15051567
Abstract: Simple Summary A marked reduction in soluble guanylyl cyclase β1 (sGCβ1) transcript is characteristic for human glioma specimens. Restoring the expression of sGCβ1 inhibited the aggressive course of glioblastoma in an orthotopic xenograft mouse model.… read more here.
Keywords: glioblastoma; cyclase; sgc; marked reduction ... See more keywords