A single nonsynonymous mutation on ZIKV E protein-coding sequences leads to markedly increased neurovirulence in vivo
Sign Up to like & getrecommendations! Published in 2022 at "Virologica Sinica"
DOI: 10.1016/j.virs.2022.01.021
Abstract: Zika virus (ZIKV) can infect a wide range of tissues including the developmental brain of human fetus. Whether specific viral genetic variants are linked to neuropathology is incompletely understood. To address this, we have intracranially… read more here.
Keywords: single nonsynonymous; zikv; markedly increased; vivo ... See more keywords
Markedly increased duodenal villous surface apoptosis in patients taking pre‐exposure prophylaxis (PrEP) against human immunodeficiency virus
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DOI: 10.1111/his.15137
Abstract: Pre‐exposure prophylaxis (PrEP) consists of combination antiretroviral therapy and is increasingly utilized to prevent human immunodeficiency virus (HIV) in high‐risk populations. Two index cases noted during routine care showed markedly increased duodenal villous surface apoptosis… read more here.
Keywords: prophylaxis prep; exposure prophylaxis; markedly increased; pre exposure ... See more keywords
Prevalence of increased transaminases and its association with sex, age, and metabolic parameters in children and adolescents with obesity – a nationwide cross-sectional cohort study
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DOI: 10.1186/s12887-021-02747-4
Abstract: Background Childhood obesity increases the risk of non-alcoholic fatty liver disease marked by elevated alanine aminotransferase (ALT). This study investigated the prevalence of increased ALT in children and adolescents with obesity, and its associations with… read more here.
Keywords: class; age; obesity; increased alt ... See more keywords