Molecular characterization of 20 small supernumerary marker chromosome cases using array comparative genomic hybridization and fluorescence in situ hybridization
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-10466-z
Abstract: The variability of a small supernumerary marker chromosome (sSMC)-related phenotype is determined by the molecular component, the size, and shape of the marker chromosome. As fluorescence in situ hybridization has limitations regarding the resolution, efficiency,… read more here.
Keywords: marker chromosome; hybridization; marker; characterization ... See more keywords
Clinical characteristics and management of Turner patients with a small supernumerary marker chromosome
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DOI: 10.1080/09513590.2021.1911992
Abstract: Abstract Objective To summarize the clinical characteristics of Turner syndrome (TS) with a small supernumerary marker chromosome (sSMC) and discuss the clinical significance and management of TS patients with sSMC. Methods A retrospective analysis was… read more here.
Keywords: marker chromosome; positive patients; patients ssmc; supernumerary marker ... See more keywords
Marker chromosome is a strong poor prognosis factor after allogeneic HSCT for adverse‐risk AML patients
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DOI: 10.1111/ejh.13495
Abstract: Chromosome analysis is necessary for the risk classification of acute myeloid leukemia (AML). Marker chromosome (MC) is a fragmented chromosome whose origin cannot be identified from other chromosomes and originates from marked genomic instability. Although… read more here.
Keywords: risk; poor prognosis; marker chromosome; aml ... See more keywords
Complex Small Supernumerary Marker Chromosome Leading to Partial 4q/21q Duplications: Clinical Implication and Review of the Literature
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DOI: 10.1159/000494682
Abstract: Complex small marker chromosomes (sSMCs) consist of chromosomal material derived from more than 1 chromosome. Complex sSMCs derived from chromosomes 4 and 21 are rare, with only 7 cases reported. Here, we describe a patient… read more here.
Keywords: marker chromosome; complex small; 21q duplications; chromosome ... See more keywords