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Published in 2025 at "Statistics in Medicine"
DOI: 10.1002/sim.70048
Abstract: The practice of using a surrogate marker to replace a primary outcome in clinical studies has become widespread. Typically, the primary outcome requires long‐term patient follow‐up, is expensive, or is invasive or burdensome for patients…
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Keywords:
using surrogate;
marker;
surrogate marker;
marker evaluation ... See more keywords
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Published in 2019 at "Translational andrology and urology"
DOI: 10.21037/tau.2019.01.16
Abstract: Serum testosterone values vary considerably with little correlation to intratesticular testosterone (ITT). ITT is approximately ~100 times that of serum testosterone and is critical for spermatogenesis. Unfortunately, the only method to accurately measure ITT is…
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Keywords:
serum;
insulin like;
testosterone;
like factor ... See more keywords