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   Articles with "marker gene" as a keyword



Predicting the Functional Potential of the Microbiome from Marker Genes Using PICRUSt.

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recommendations! Published in 2018 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-8728-3_11

Abstract: Marker-gene sequencing is a cost-effective method of taxonomically profiling microbial communities. Unlike metagenomic approaches, marker-gene sequencing does not provide direct information about the functional genes that are present in the genomes of community members. However,… read more here.

Keywords: functional potential; reference; picrust; marker ... See more keywords

Using marker gene analysis instead of mixed lymphocyte reaction assay for identification of functional CD4+FOXP3+ regulatory T cells

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recommendations! Published in 2017 at "Biotechnology Letters"

DOI: 10.1007/s10529-017-2498-8

Abstract: ObjectiveTo establish a quick analytical method using quantitative PCR for marker gene analysis to identify the functions of iTreg cells and subsequently curtail the harvest time for iTreg cells.ResultsThe data from the marker gene analysis… read more here.

Keywords: gene; marker gene; itreg cells; gene analysis ... See more keywords

metagenomeFeatures: an R package for working with 16S rRNA reference databases and marker-gene survey feature data

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recommendations! Published in 2019 at "Bioinformatics"

DOI: 10.1093/bioinformatics/btz136

Abstract: We developed the metagenomeFeatures R Bioconductor package along with annotation packages for three 16S rRNA databases (Greengenes, RDP, and SILVA) to facilitate working with 16S rRNA databases and marker-gene survey feature data. The metagenomeFeatures package… read more here.

Keywords: 16s rrna; marker gene; gene survey; working 16s ... See more keywords

B-134 Evaluation of marker gene-based in silico antimicrobial resistance (AMR) prediction tools

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recommendations! Published in 2025 at "Clinical Chemistry"

DOI: 10.1093/clinchem/hvaf086.529

Abstract: Monitoring and surveillance of antimicrobial resistance (AMR) is important procedure in clinically patient management and epidemiologically public health. Conventionally such culture based tools as disk diffusion method or broth dilution method for antibiotic susceptibility test… read more here.

Keywords: amr; culture; prediction tools; marker gene ... See more keywords

Unassigning bacterial species for microbiome studies

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recommendations! Published in 2024 at "mSystems"

DOI: 10.1128/msystems.00515-24

Abstract: ABSTRACT The method of 16S rRNA marker gene sequencing has fueled microbiome research and continues to be relevant. A perceived weakness of the method is that taxonomic assignments are not possible to make at the… read more here.

Keywords: species membership; species level; marker gene; 16s rrna ... See more keywords

Marker genes as predictors of shared genomic function

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recommendations! Published in 2019 at "BMC Genomics"

DOI: 10.1186/s12864-019-5641-1

Abstract: BackgroundAlthough high-throughput marker gene studies provide valuable insight into the diversity and relative abundance of taxa in microbial communities, they do not provide direct measures of their functional capacity. Recently, scientists have shown a general… read more here.

Keywords: marker genes; coding gene; marker gene; marker ... See more keywords

Alveolar type 2 cells marker gene SFTPC inhibits epithelial-to-mesenchymal transition by upregulating SOX7 and suppressing WNT/β-catenin pathway in non-small cell lung cancer

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recommendations! Published in 2024 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2024.1448379

Abstract: Introduction Surfactant Protein C gene (SFTPC) is a marker gene of alveolar type 2 cells (AT2), which are the key structures of alveoli. Mutations or deletions in SFTPC cause idiopathic pulmonary fibrosis (IPF). Importantly, IPF… read more here.

Keywords: gene; marker gene; expression; alveolar type ... See more keywords

An Efficient Marker Gene Excision Strategy Based on CRISPR/Cas9-Mediated Homology-Directed Repair in Rice

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recommendations! Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23031588

Abstract: In order to separate transformed cells from non-transformed cells, antibiotic selectable marker genes are usually utilized in genetic transformation. After obtaining transgenic plants, it is often necessary to remove the marker gene from the plant… read more here.

Keywords: crispr cas9; marker; marker gene; gene ... See more keywords