Unraveling Structural Alerts in Marketed Drugs for Improving Adverse Outcome Pathway Framework of Drug-Induced QT Prolongation
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DOI: 10.3390/ijms24076771
Abstract: In pharmaceutical treatment, many non-cardiac drugs carry the risk of prolonging the QT interval, which can lead to fatal cardiac complications such as torsades de points (TdP). Although the unexpected blockade of ion channels has… read more here.
Keywords: drug induced; prolongation; induced prolongation; marketed drugs ... See more keywords