Thermal injury of the skin induces G-CSF-dependent attenuation of EPO-mediated STAT signaling and erythroid differentiation arrest in mice.
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DOI: 10.1016/j.exphem.2017.08.005
Abstract: Inflammation-mediated impairment of erythropoiesis plays a central role in the development of the anemia of critical illness (ACI). ACI develops despite elevation of endogenous erythropoietin (EPO), does not respond to exogenous erythropoietin (EPO) supplementation, and… read more here.
Keywords: marrow erythroid; mice; erythroid differentiation; bone marrow ... See more keywords