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Abstract 522: IL-10 Knockout Bone Marrow Fibroblast Progenitor Cells-derived Exosomes Activate Cardiac Fibroblast and Exaggerate Pressure Overload-induced Fibrosis in Mice Heart

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Published in 2019 at "Circulation Research"

DOI: 10.1161/res.125.suppl_1.522

Abstract: Background: Inflammatory mediators play important role in cardiac remodeling. In heart, fibrosis is mainly mediated by activated fibroblasts (myofibroblasts), however, origin of myofibroblasts in diseased heart remains unclear. Recently, we have shown that bone marrow… read more here.

Keywords: heart; fibrosis; fibroblast; cardiac fibroblast ... See more keywords