Immune thrombocytopenia is associated with persistently deranged fibrosis-related seromarker profiles but low bone marrow fibrosis grades: A 2-year observational study on thrombopoietin receptor agonist treatment
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DOI: 10.1080/09537104.2017.1411586
Abstract: Abstract Bone marrow (BM) fibrosis is a potential side effect of thrombopoietin receptor agonist (TPO-RA) treatment. We aimed to investigate stromal seromarker profiles and growth factors in order to elucidate pathogenic and dynamic aspects of… read more here.
Keywords: marrow fibrosis; fibrosis; treatment; thrombopoietin receptor ... See more keywords
Does Bone Marrow Fibrosis Play a Role in the Prognostication of Newly Diagnosed Polycythemia Vera Patients
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DOI: 10.1182/blood.v130.suppl_1.4184.4184
Abstract: According to the WHO 2016 revised classification of myeloproliferative disorders, bone marrow biopsy is included among the major criteria for the diagnosis of policythemia vera (PV). However, the prognostic role of marrow fibrosis at baseline… read more here.
Keywords: marrow fibrosis; consultancy speakers; speakers bureau; consultancy ... See more keywords
Bone marrow fibrosis associated with long-term imatinib therapy: resolution after switching to a second-generation TKI.
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DOI: 10.1182/bloodadvances.2018027516
Abstract: Bone marrow fibrosis may be a late reversible toxicity of high-dose imatinib therapy in chronic myeloid leukemia. read more here.
Keywords: marrow fibrosis; imatinib therapy; bone marrow;
Coexisting of bone marrow fibrosis, dysplasia and an X chromosomal abnormality in chronic neutrophilic leukemia with CSF3R mutation: a case report and literature review
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DOI: 10.1186/s12885-018-4236-6
Abstract: BackgroundChronic neutrophilic leukemia (CNL) is a rare myeloproliferative neoplasm (MPN) with less than 40 cases of patients being reported or clinically suspected meeting with 2008 World Health Organization (“WHO”) diagnostic criteria. The current diagnosis of… read more here.
Keywords: marrow fibrosis; bone marrow; csf3r; mutation ... See more keywords
Myelodysplastic Syndromes with Bone Marrow Fibrosis: An Update
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DOI: 10.3343/alm.2022.42.3.299
Abstract: Myelodysplastic syndrome (MDS) is a diverse hematological malignancy with a wide spectrum of presentations and implications. Treatment strategies for patients with MDS heavily rely on prognostic scoring systems, such as the revised international prognostic scoring… read more here.
Keywords: syndromes bone; bone marrow; myelodysplastic syndromes; patients mds ... See more keywords
Bone Marrow Fibrosis at Diagnosis and during the Course of Disease Is Associated with TP53 Mutations and Adverse Prognosis in Primary Myelodysplastic Syndrome
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DOI: 10.3390/cancers14122984
Abstract: Simple Summary To understand the role of bone marrow fibrosis and its molecular changes in myelodysplastic syndrome, we retrospectively analyzed data from 814 patients. Older age, lower hemoglobin, unfavorable karyotype and higher BM blast were… read more here.
Keywords: myelodysplastic syndrome; prognosis; diagnosis; bone marrow ... See more keywords
Novel Usefulness of Krebs von den Lungen 6 (KL-6) with Hemoglobin and Lactate Dehydrogenase for Assessing Bone Marrow Fibrosis
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DOI: 10.3390/diagnostics12030628
Abstract: Bone marrow fibrosis (BMF) is manually assessed by reticulin and trichrome stain of bone marrow (BM) biopsy and graded on a semi-quantitative scale. Krebs von den Lungen 6 (KL-6) and Mac-2 binding protein glycosylation isomer… read more here.
Keywords: marrow fibrosis; krebs von; bone; bone marrow ... See more keywords