METTL3 mediates bone marrow mesenchymal stem cell adipogenesis to promote chemoresistance in acute myeloid leukaemia
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DOI: 10.1002/2211-5463.13165
Abstract: Adipogenesis of bone marrow mesenchymal stem cells (MSCs) promotes chemoresistance of acute myeloid leukaemia (AML) cells. MSCs from AML patients (AML‐MSCs) display enhanced adipogenesis compared with bone marrow MSCs from healthy donors. However, the precise… read more here.
Keywords: adipogenesis; chemoresistance acute; bone marrow; marrow mesenchymal ... See more keywords
A comparative study of mouse bone marrow mesenchymal stem cells isolated using three easy‐to‐perform approaches
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DOI: 10.1002/2211-5463.13493
Abstract: Mouse bone marrow mesenchymal stem cells (mBM‐MSCs) are important for preclinical tissue regeneration and repair studies. In the present study, we isolated mBM‐MSCs using three easy‐to‐perform methods (whole bone marrow‐adherent culture, density‐gradient centrifugation, and bone… read more here.
Keywords: marrow mesenchymal; bone marrow; bone; mouse bone ... See more keywords
Bone marrow mesenchymal stem cells‐derived exosomes mediate nuclear receptor coactivator‐3 expression in osteoblasts by delivering miR‐532‐5p to influence osteonecrosis of the femoral head development
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DOI: 10.1002/cbin.11902
Abstract: Exosomes (Exo) originated from bone marrow mesenchymal stem cells (BMSCs) have therapeutic impacts on osteonecrosis of the femoral head (ONFH), and microRNA (miR)‐532‐5p has been confirmed to participate in ONFH progression. In the research, it… read more here.
Keywords: marrow mesenchymal; bone marrow; delivering mir; mesenchymal stem ... See more keywords
Uremic Serum Impairs Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stromal Cells
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DOI: 10.1002/jcp.25732
Abstract: Chronic Kidney Disease‐Mineral and Bone Disorder (CKD‐MBD) is characterized by an increased fracture risk. Bone marrow mesenchymal stromal cells (BMSCs) may be involved in the pathogenesis of bone disease and, in view of their promising… read more here.
Keywords: mesenchymal stromal; bone; osteogenic differentiation; marrow mesenchymal ... See more keywords
Bone marrow mesenchymal stem cells‐derived conditioned medium protects cardiomyocytes from hypoxia/reoxygenation‐induced injury through Notch2/mTOR/autophagy signaling
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28530
Abstract: Bone marrow mesenchymal stem cells (BMSC) can ameliorate ischemic injury of various tissues. However, the molecular mechanisms involved remain to be clarified. In this study, we intend to investigate the effects of BMSC‐derived conditioned medium… read more here.
Keywords: induced injury; marrow mesenchymal; mtor; mesenchymal stem ... See more keywords
Effects of local injection and intravenous injection of allogeneic bone marrow mesenchymal stem cells on the structure and function of damaged anal sphincter in rats
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.3079
Abstract: Anal sphincter injury leads to damage to the anal structure and functions and has been identified as a major risk factor for fecal incontinence. Bone marrow mesenchymal stem cells (BMSCs) with capacities of multidifferentiation, paracrine,… read more here.
Keywords: anal sphincter; bone marrow; injection; marrow mesenchymal ... See more keywords
Bone marrow mesenchymal stem cells repair hexavalent chromium‐induced testicular injury by regulating autophagy and ferroptosis mediated by the AKT/mTOR pathway in rats
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DOI: 10.1002/tox.23713
Abstract: There is no ideal therapy for testicular damage induced by Cr(VI); however, bone marrow mesenchymal stem cells (BMSCs) transplantation may be a promising therapy. A Cr(VI) solution was administered to rats by intraperitoneal injection for… read more here.
Keywords: marrow mesenchymal; bone marrow; group; mesenchymal stem ... See more keywords
Photobiomodulation treatments drive osteogenic versus adipocytic fate of bone marrow mesenchymal stem cells reversing the effects of hyperglycemia in diabetes
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DOI: 10.1007/s10103-022-03553-9
Abstract: Diabetes mellitus (DM) is a chronic metabolic disease that affects bone metabolism, which can be related to a reduced osteogenic potential of bone marrow mesenchymal stem cells (BM-MSCs). MSCs from diabetic rats (dBM-MSC) have shown… read more here.
Keywords: bone marrow; marrow mesenchymal; mesenchymal stem; stem cells ... See more keywords
In Vivo Effects of Human Bone Marrow Mesenchymal Stromal Cells on the Development of Experimental B16 Melanoma in Mice
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DOI: 10.1007/s10517-020-04753-5
Abstract: Experiments on F1(CBA×C57BL/6) mice with experimental metastatic melanoma B16 F10 showed that single intravenous injection of xenogeneic bone marrow mesenchymal stromal cells (BM-MSC) in a dose of 10 6 cells/mouse significantly increased 100-day survival rate… read more here.
Keywords: b16; mesenchymal stromal; stromal cells; mice ... See more keywords
Tenocyte proliferation and migration promoted by rat bone marrow mesenchymal stem cell-derived conditioned medium
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DOI: 10.1007/s10529-017-2446-7
Abstract: ObjectivesTo investigate the impact of secreted factors of rat bone marrow mesenchymal stem cells (MSCs) on the proliferation and migration of tenocytes and provide evidence for the development of MSC-based therapeutic methods of tendon injury.ResultsRat… read more here.
Keywords: proliferation; migration; mesenchymal stem; marrow mesenchymal ... See more keywords
Bioactive polypeptide hydrogels modified with RGD and N-cadherin mimetic peptide promote chondrogenic differentiation of bone marrow mesenchymal stem cells
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DOI: 10.1007/s11426-020-9772-0
Abstract: Cell-material and cell-cell interactions represent two crucial aspects of the regulation of cell behavior. In the present study, poly (L-glutamic acid) (PLG) hydrogels were prepared by catalyst-free click crosslinking via a strain-promoted azide-alkyne cycloaddition (SPAAC)… read more here.
Keywords: plg; marrow mesenchymal; mimetic peptide; cadherin mimetic ... See more keywords