Articles with "marrow stromal" as a keyword



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Allogeneic chondrogenically differentiated human bone marrow stromal cells do not induce dendritic cell maturation

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Published in 2018 at "Journal of Tissue Engineering and Regenerative Medicine"

DOI: 10.1002/term.2682

Abstract: Bone marrow stromal cell (BMSC)‐mediated endochondral bone formation may be a promising alternative to the current gold standards of autologous bone transplantation, in the development of novel methods for bone repair. Implantation of chondrogenically differentiated… read more here.

Keywords: hbmsc pellets; marrow stromal; bone; cell ... See more keywords
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Derivation of Fate-Committed Schwann Cells from Bone Marrow Stromal Cells of Adult Rats.

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Published in 2018 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-7649-2_9

Abstract: Our goal is to derive phenotypically stable Schwann cells from bone marrow stromal cells (BMSCs) for use in transplantation studies of central/peripheral nerve injuries. With the adult rat as model, here we describe steps that… read more here.

Keywords: marrow stromal; schwann cells; stromal cells; cells bone ... See more keywords
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Aspirin in stroke patients modifies the immunomodulatory interactions of marrow stromal cells and monocytes

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Published in 2019 at "Brain Research"

DOI: 10.1016/j.brainres.2019.06.017

Abstract: BACKGROUND AND OBJECTIVE Most stroke patients are prescribed aspirin (ASA) to adjust blood coagulability. Marrow stromal cells (MSCs) are being tested in clinical trials for stroke patients who likely are prescribed aspirin. One of the… read more here.

Keywords: marrow stromal; stromal cells; mscs; stroke patients ... See more keywords
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Global Transcriptomic Profiling of the Bone Marrow Stromal Microenvironment during Postnatal Development, Aging, and Inflammation.

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Published in 2019 at "Cell reports"

DOI: 10.1016/j.celrep.2019.11.004

Abstract: Bone marrow (BM) stromal cells provide the regulatory framework for hematopoiesis and contribute to developmental stage-specific niches, such as those preserving hematopoietic stem cells. Despite advances in our understanding of stromal function, little is known… read more here.

Keywords: global transcriptomic; marrow stromal; transcriptomic profiling; bone marrow ... See more keywords
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Thrombin inhibitor argatroban modulates bone marrow stromal cells behaviors and promotes osteogenesis through canonical Wnt signaling.

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Published in 2021 at "Life sciences"

DOI: 10.1016/j.lfs.2021.119073

Abstract: AIMS Coagulation is a common event that play a double-edged role in physiological and pathological process. Anti-coagulation methods were applied in joint surgery or scaffolds implantation to encourage new vascular formation and avoid coagulation block.… read more here.

Keywords: argatroban; coagulation; inhibitor argatroban; marrow stromal ... See more keywords
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Hypoxia depletes contaminating CD45+ hematopoietic cells from murine bone marrow stromal cell (BMSC) cultures: Methods for BMSC culture purification.

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Published in 2021 at "Stem cell research"

DOI: 10.1016/j.scr.2021.102317

Abstract: Culture expanded bone marrow stromal cells (BMSCs) are easily isolated, can be grown rapidly en masse, and contain both skeletal stem cells (SSCs) and multipotent mesenchymal progenitors (MMPs). Despite this functional heterogeneity, BMSCs continue to… read more here.

Keywords: marrow stromal; stromal cells; cd45 hematopoietic; culture ... See more keywords
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Prostaglandin E2 inhibits matrix mineralization by human bone marrow stromal cell-derived osteoblasts via Epac-dependent cAMP signaling

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-02650-y

Abstract: The osteoinductive properties of prostaglandin E2 (PGE2) and its signaling pathways have led to suggestions that it may serve as a potential therapeutic strategy for bone loss. However, the prominence of PGE2 as an inducer… read more here.

Keywords: marrow stromal; stromal cell; human bone; bone ... See more keywords
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Extracellular vesicles from bone marrow stromal cells reduce the impact of stroke on glial cell activation and blood brain‐barrier permeability via a putative miR‐124/PRX1 signalling pathway

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Published in 2022 at "European Journal of Neuroscience"

DOI: 10.1111/ejn.15669

Abstract: Ischaemic stroke (IS) is a cerebrovascular disease caused by cerebral infarction and cerebral artery occlusion. In this study, we proposed that EVs from bone marrow stromal cells (BMSCs) could reduce the impact of stroke by… read more here.

Keywords: mir 124; bone marrow; marrow stromal; permeability ... See more keywords
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Human Bone Marrow Stromal Cell Exosomes Ameliorate Periodontitis

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Published in 2022 at "Journal of Dental Research"

DOI: 10.1177/00220345221084975

Abstract: Human bone marrow stromal cell (hBMSC)–derived exosomes are promising therapeutics for inflammatory diseases due to their unique microRNA (miRNA) and protein cargos. Periodontal diseases often present with chronicity and corresponding exuberant inflammation, which leads to… read more here.

Keywords: cell; human bone; bone marrow; hbmsc ... See more keywords
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Bone marrow stromal cell therapy for ischemic stroke: A meta-analysis of randomized control animal trials

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Published in 2017 at "International Journal of Stroke"

DOI: 10.1177/1747493016676617

Abstract: Background Results of animal studies assessing efficacy of bone marrow stromal cell therapy for ischemic stroke remain inconsistent. Aims The aims are to assess efficacy of bone marrow stromal cell therapy for ischemic stroke in… read more here.

Keywords: stromal cell; marrow stromal; therapy; bone marrow ... See more keywords
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Altered Genomic and Epigenetic Profiling of Myeloma Bone Marrow Stromal Cells Identifies Targets for Current and Future Immunotherapeutic Approaches

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Published in 2019 at "Blood"

DOI: 10.1182/blood-2019-131243

Abstract: Background: Novel drug discoveries have shifted the treatment paradigms of most hematological malignancies including multiple myeloma (MM), but minimal residual disease and drug resistance underlie relapses in MM. Although many genetic and epigenetic alterations regulate… read more here.

Keywords: marrow stromal; compared bmsc; bmsc; stromal cells ... See more keywords