Organoarsenical tolerance in Sphingobacterium wenxiniae, a bacterium isolated from activated sludge.
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DOI: 10.1111/1462-2920.15599
Abstract: Organoarsenicals enter the environment from biogenic and anthropogenic sources. Trivalent inorganic arsenite (As(III)) is microbially methylated to more toxic methylarsenite (MAs(III)) and dimethylarsenite (DMAs(III)) that oxidize in air to MAs(V) and DMAs(V). Sources include the… read more here.
Keywords: mas iii; iii; isolated activated; sphingobacterium wenxiniae ... See more keywords
Functional characterization of the methylarsenite-inducible arsRM operon from Noviherbaspirillum denitrificans HC18.
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DOI: 10.1111/1462-2920.15909
Abstract: Microbial arsenic methylation by arsenite (As(III)) S-adenosylmethionine methyltransferases (ArsMs) can produce the intermediate methylarsenite (MAs(III)), which is highly toxic and is used by some microbes as an antibiotic. Other microbes have evolved mechanisms to detoxify… read more here.
Keywords: methylation; noviherbaspirillum denitrificans; denitrificans hc18; arsrm operon ... See more keywords
ArsZ from Ensifer adhaerens ST2 is a novel methylarsenite oxidase.
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DOI: 10.1111/1462-2920.15983
Abstract: Trivalent methylarsenite (MAs(III)) produced by biomethylation is more toxic than inorganic arsenite (As(III)). Hence, MAs(III) has been proposed to be a primordial antibiotic. Other bacteria evolved mechanisms to detoxify MAs(III). In this study, the molecular… read more here.
Keywords: mas iii; arsz; oxidase; adhaerens st2 ... See more keywords
A PadR family transcriptional repressor controls transcription of a trivalent metalloid resistance operon of Azospirillum halopraeferens strain Au 4.
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DOI: 10.1111/1462-2920.16147
Abstract: Methylarsenite [MAs(III)] is a highly toxic arsenical produced by some microbes as an antibiotic. In this study, we demonstrate that a PadR family transcriptional regulator, PadRars , from Azospirillum halopraeferens strain Au 4 directly binds… read more here.
Keywords: padr family; transcription; ars operon; mas iii ... See more keywords
Methylarsenite is a broad-spectrum antibiotic disrupting cell wall biosynthesis and cell membrane potential.
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DOI: 10.1111/1462-2920.16309
Abstract: Methylarsenite (MAs(III)), a product of arsenic biomethylation or bioreduction of methylarsenate (MAs(V)), has been proposed as a primitive antibiotic. However, the antibacterial property and the bactericidal mechanism of MAs(III) remain largely unclear. In this study,… read more here.
Keywords: cell wall; iii; mas iii; subtilis 168 ... See more keywords