Hydrotrifluoroacetylation of Alkenes via Designer Masked Acyl Reagents.
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DOI: 10.1021/jacs.3c04294
Abstract: Because of its impressive ability to promote pharmaceutical activity, the introduction of trifluoromethylacyl (CF3CO) functionality into organic compounds has become an important and growing research area. Although various protocols have been developed to access trifluoroketones,… read more here.
Keywords: designer masked; via designer; alkenes via; hydrotrifluoroacetylation alkenes ... See more keywords
Synthesis of (2-Nitro-1-AfAlemphenylethyl)malononitriles by Michael Addition of Masked Acyl Cyanides to Nitroalkenes
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DOI: 10.1055/s-0041-1738437
Abstract: A highly efficient method has been developed for the synthesis of (2-nitro-1-phenylethyl)malononitriles through a Michael addition reaction between substituted nitroolefins and masked acyl cyanide reagents, serving as carbon monoxide equivalents. Under mild conditions, the reaction… read more here.
Keywords: synthesis nitro; malononitriles michael; michael addition; masked acyl ... See more keywords