Stereoselective Syntheses of Masked β-Amino Acid Containing Phthalides
Sign Up to like & getrecommendations! Published in 2022 at "Helvetica chimica acta"
DOI: 10.1002/hlca.202200110
Abstract: We herein report a protocol for the asymmetric aldol-initiated cascade addition of isoxazolidin-5-ones to ortho-cyanobenzaldehydes by using Takemoto’s bifunctional organocatalyst. This approach allows for the synthesis of various novel β2,2-amino acid-phthalide conjugates with good enantio-… read more here.
Keywords: acid containing; masked amino; syntheses masked; acid ... See more keywords
Metal-free and benign approach for the synthesis of dihydro-5′H-spiro[benzo[c]chromene-8,4′-oxazole]-5′,6(7H)-dione scaffolds as masked amino acids
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DOI: 10.1039/c9gc00428a
Abstract: Eco-friendly one-pot synthesis of new masked amino acids is described. read more here.
Keywords: synthesis; benign approach; masked amino; amino acids ... See more keywords