Targeting MASLD and MASH in the US Hispanic/Latino Population: A Review.
Sign Up to like & getrecommendations! Published in 2025 at "JAMA internal medicine"
DOI: 10.1001/jamainternmed.2025.4769
Abstract: Importance The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) in the US is highest among Hispanic/Latino individuals. Their risk of developing metabolic dysfunction-associated steatohepatitis (MASH) with fibrosis, cirrhosis with progression to hepatocellular carcinoma and… read more here.
Keywords: latino population; hispanic latino; risk; latino ... See more keywords
Serum adropin is unaltered in adolescents with histology-confirmed steatotic liver disease.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of pediatric gastroenterology and nutrition"
DOI: 10.1002/jpn3.12423
Abstract: OBJECTIVES Metabolic dysfunction-associated steatotic liver disease (MASLD) in adolescents is increasing. Adropin is a liver-derived peptide involved in glucose and lipid homeostasis that was shown to be reduced in adults with metabolic disorders and cardiovascular… read more here.
Keywords: serum adropin; disease; adropin; histology ... See more keywords
The Rising Global Burden of MASLD and Other Metabolic Diseases (2000–2021)
Sign Up to like & getrecommendations! Published in 2025 at "United European Gastroenterology Journal"
DOI: 10.1002/ueg2.70072
Abstract: ABSTRACT Background Metabolic diseases are a public health threat to diverse populations worldwide. This study aims to update the epidemiological trends of metabolic diseases across regions and sociodemographic stratifications using the Global Burden of Diseases… read more here.
Keywords: 2000 2021; masld; global burden; metabolic diseases ... See more keywords
Comparative application of MAFLD and MASLD diagnostic criteria on NAFLD patients: insights from a single-center cohort
Sign Up to like & getrecommendations! Published in 2025 at "Clinical and Experimental Medicine"
DOI: 10.1007/s10238-024-01553-3
Abstract: The diagnostic criteria for Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) and Metabolic Associated Steatotic Liver Disease (MASLD) aim to refine the classification of fatty liver diseases previously grouped under Non-Alcoholic Fatty Liver Disease (NAFLD). This… read more here.
Keywords: fibrosis; mafld masld; nafld patients; masld ... See more keywords
Association between metabolic dysfunction-associated steatotic liver disease and risk of urolithiasis: an updated systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2024 at "Internal and Emergency Medicine"
DOI: 10.1007/s11739-024-03705-5
Abstract: Epidemiological studies have reported an association between metabolic dysfunction-associated steatotic liver disease (MASLD) and the risk of urolithiasis. However, the magnitude of the risk and whether this risk varies with the severity of MASLD remains… read more here.
Keywords: urolithiasis; meta analysis; risk; association ... See more keywords
Hepatic AKAP1 deficiency exacerbates diet-induced MASLD by enhancing GPAT1-mediated lysophosphatidic acid synthesis
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-58790-7
Abstract: Metabolic dysfunction-associated steatotic liver disease (MASLD), closely associated with obesity, can progress to metabolic dysfunction-associated steatohepatitis when the liver undergoes overt inflammatory damage. A-kinase anchoring protein 1 (AKAP1) has been shown to control lipid accumulation… read more here.
Keywords: gpat1; hepatic akap1; akap1 deficiency; masld ... See more keywords
Effect of smartphone-assisted lifestyle intervention in MASLD patients: a randomized controlled trial
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-64988-4
Abstract: Metabolic dysfunction-associated steatotic liver disease (MASLD) is emerging globally as a significant problem. The mainstay of treatment is lifestyle intervention (LSI). We hypothesized that providing information regarding LSI and MASLD through a social media application… read more here.
Keywords: lifestyle intervention; masld; masld patients; randomized controlled ... See more keywords
MASLD does not affect fertility and senolytics fail to prevent MASLD progression in male mice
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-67697-0
Abstract: Senescent cells have been linked to the pathogenesis of metabolic dysfunction-associated steatotic liver disease (MASLD). However, the effectiveness of senolytic drugs in reducing liver damage in mice with MASLD is not clear. Additionally, MASLD has… read more here.
Keywords: mice; fertility; liver damage; male mice ... See more keywords
Serum Tsukushi level is negatively associated with cholesterol efflux capacity in metabolic dysfunction-associated steatotic liver disease: a cross-sectional study
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-06431-w
Abstract: Background Tsukushi (TSK), a recently identified hepatokine, has been shown to affect systemic cholesterol homeostasis and reduce HDL cholesterol (HDL-C) in murine studies. We have investigated whether TSK is associated with HDL-C and HDL function… read more here.
Keywords: efflux capacity; cholesterol; hdl; cholesterol efflux ... See more keywords
A potential age-independent MASLD-related liver fibrosis index based on metabolic profiling
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DOI: 10.1038/s41598-025-18172-x
Abstract: The burden of metabolic dysfunction-associated steatotic liver disease (MASLD) is of immediate concern, as its prevalence is increasing worldwide. MASLD often progresses to liver fibrosis, posing significant health risks. Age-independent, noninvasive tools to evaluate fibrosis… read more here.
Keywords: age; fibrosis; liver fibrosis; index ... See more keywords
Association of noninvasive tests of liver fibrosis with chronic kidney disease in MASLD: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-26752-0
Abstract: Metabolic dysfunction-associated steatotic liver disease (MASLD) is an emerging risk factor for chronic kidney disease (CKD). While liver biopsy is the gold standard for assessing fibrosis, noninvasive tests (NITs)—including fibrosis-4 (FIB-4), nonalcoholic fatty liver disease… read more here.
Keywords: disease; kidney disease; disease masld; association ... See more keywords