Probiotic Mixture Ameliorates a Diet-Induced MASLD/MASH Murine Model through the Regulation of Hepatic Lipid Metabolism and the Gut Microbiome
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DOI: 10.1021/acs.jafc.3c08910
Abstract: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent metabolic disease that has no effective treatment. Our proprietary probiotic mixture, Prohep, has been proven in a previous study to be helpful in reducing hepatocellular carcinoma… read more here.
Keywords: prohep; model; masld mash; induced masld ... See more keywords
Meta-analysis of shotgun sequencing of gut microbiota in obese children with MASLD or MASH
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DOI: 10.1080/19490976.2025.2508951
Abstract: ABSTRACT Alterations in the gut microbiome affect the development and severity of metabolic dysfunction-associated steatotic liver disease (MASLD) or metabolic dysfunction-associated steatohepatitis (MASH). We analyzed microbiomes of obese children with and without MASLD, MASH, and… read more here.
Keywords: obese children; gut microbiome; children masld; mash ... See more keywords
8480 TIX100, a Novel Small Molecule for the Treatment of MASLD/MASH
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the Endocrine Society"
DOI: 10.1210/jendso/bvae163.045
Abstract: Abstract Disclosure: S. Jo: None. J. Chen: None. G. Jing: None. K.M. Habegger: None. A. Shalev: Other; Self; TIXiMED, Inc. Founder & CSO. Metabolic dysfunction-associated steatotic liver disease (MASLD) and steatohepatitis (MASH) (aka NAFLD and… read more here.
Keywords: treatment; masld mash; masld; tix100 ... See more keywords
Efficacy and safety of resmetirom in MASLD and MASH: network meta-analysis of randomized clinical trials
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DOI: 10.1515/jbcpp-2024-0140
Abstract: Abstract Introduction Metabolic-Associated Steatohepatitis-Related Liver Disease (MASLD) and, its progressive form, Metabolic-Associated Steatohepatitis (MASH) pose significant global health challenges. Current therapeutic strategies targeting metabolic abnormalities have shown promise but lack specificity for the liver. Thyroid… read more here.
Keywords: mash; masld mash; network meta; resmetirom ... See more keywords
Extracellular RNAs in Liquid Biopsy: Applications in MASLD and MASH Diagnosis and Monitoring
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DOI: 10.3390/diagnostics15182346
Abstract: Metabolic dysfunction-associated steatotic liver disease (MASLD) is an increasingly prevalent condition linked to obesity, diabetes, and metabolic syndrome, and can progress to fibrosis, cirrhosis, and hepatocellular carcinoma. Current diagnostic standards such as liver biopsy are… read more here.
Keywords: biopsy applications; liquid biopsy; masld mash; extracellular rnas ... See more keywords
Manifestation and Progression of Metabolic Dysfunction-Associated Steatotic Liver Disease in a Predominately African American Population at a Multi-Specialty Healthcare Organization
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DOI: 10.3390/healthcare12151478
Abstract: African Americans (AA) have a high incidence of risk factors associated with MASLD (metabolic dysfunction-associated steatotic liver disease); the AA population has a lower incidence of MASLD and MASH (metabolic-associated steatotic hepatitis) than Caucasian and… read more here.
Keywords: disease; progression; population; masld mash ... See more keywords
Recent Advances in miRNA-Based Therapy for MASLD/MASH and MASH-Associated HCC
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DOI: 10.3390/ijms252212229
Abstract: Simple Summary Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease, affects over one billion adults worldwide. It can progress to more severe conditions, like metabolic dysfunction-associated steatohepatitis (MASH), cirrhosis, and… read more here.
Keywords: hcc recent; mirna based; mash; masld mash ... See more keywords
Polygenic Risk Score for Metabolic Dysfunction-Associated Steatotic Liver Disease and Steatohepatitis: A Narrative Review
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DOI: 10.3390/ijms26115164
Abstract: Metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH) are spreading worldwide as the most critical causes of cirrhosis and hepatocellular carcinoma (HCC). Thus, improving the screening and managing strategies for patients with… read more here.
Keywords: dysfunction associated; masld mash; metabolic dysfunction; review ... See more keywords